Assessment of autonomic nervous system function in a patient suffering from multiple sclerosis - a case study

Karolina Kubiak, Martyna Lamtych, Klaudia Kwiatkowska, Nataliia Badiuk

Abstract


Background: Multiple sclerosis (MS) is a chronic demyelinating disease of the nervous system. In its course, there are many motor and non-motor disorders, including the autonomic system disorders. They are characterized by an increase or decrease in the activity of the autonomic nervous system. The course of the disease is most often multi-phase, there are periods of remission and exacerbation. The aim of the study is to assess cardiovascular parameters and heart rate variability in response to orthostatic stimuli in a patient with multiple sclerosis.
Material and Method: A 48-year-old woman suffering from multiple sclerosis for 10 years (a form of secondary progressive disease) participated in the study. A study was carried out for cardiovascular response and heart rate variability in response to orthostatic stimuli. For this purpose, the Task Force Monitor system was used, which is a non-invasive method that allows the assessment of hemodynamic parameters such as heart rate, systolic blood pressure, diastolic blood pressure, and peripheral vascular resistance. Spectral heart rate variability (HRV) analysis was also used to assess the function of the autonomic nervous system. The evaluated parameters were: low-frequency component (LF), high-frequency (HF) and sympathetic-parasympathetic balance factor (LF / HF).
Results: In the rest position, an autonomic balance shift was observed towards sympathetic domination. After performing the tilt test, the patient had an after pionization drop in blood pressure (orthostatic hypotension) as well as vascular resistance.
Conclusions: The analysis of the case study shows that in multiple sclerosis there may be disorders of the autonomic nervous system manifested by abnormal regulation of arterial pressure in a vertical position.

Keywords


multiple sclerosis; autonomic dysfunction; dysautonomy

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References


Świątek M.: Stwardnienie rozsiane – przyczyny, rodzaje, objawy i leczenie. Gazeta Farmaceutyczna. Styczeń 2016

Zakrzewska – Pniewska B. Z: Elektrofizjologiczne metody oceny dysautonomii

w chorobach układu nerwowego. Polski Przegląd Neurologiczny, 2008:4:2

Zalewski P., Słomiński K., Klawe J.J., Tafil-Klawe M.: Ocena czynnościowa autonomicznego układu nerwowego z użyciem systemu Task Force Monitor. Acta Bio-Optica et InformaticaMedica 3/2008, vol. 14

Damla O, AltugC,PinarKK,Alper K ,DilekIG,Kadriye A .: Heart rate variability analysis in patients with multiple sclerosis.MultSclerRelatDisord. 2018:24:64-68

Studer V, Rocchi C, Motta C, et al.: Heart rate variability is differentially altered in multiple sclerosis: implications for acute, worsening and progressive disability. MultScler J ExpTranslClin. 2017;3(2)

Flachenecker P, Wolf A, Krauser M, Hartung HP, Reiners K.: Cardiovascular autonomic dysfunction in multiple sclerosis: correlation with orthostatic intolerance.

J Neurol. 1999 Jul;246(7):578-86.




DOI: http://dx.doi.org/10.5281/zenodo.3404070

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