The influence of non-pharmacological methods in osteoporosis treatment

Agnieszka Kujawska, Małgorzata Gajos, Weronika Topka, Beniamin Szmelcer, Daria Bieniek, Aleksandra Modlińska, Marcin Kożuchowski, Radosław Perkowski, Joanna Androsiuk-Perkowska, Sylwia Ziółkowska

Abstract


Introduction
Osteoporosis is a systemic skeletal disorder which results from an imbalance in bone remodeling. The disease can occur because of failure to achieve peak bone mass and/or excessive bone resorption and/or decreased bone formation during remodelling. Multiple pathogenetic and regulatory mechanisms are responsible for these changes. In the above review, selected non-pharmacological therapies in osteoporosis are described.
Material and methods
Articles in the EBSCO database have been analyzed using keywords: osteoporosis, osteopenia, treatment. The available literature is subjectively selected. Then, the newest version of every paper was searched for.
Results
Results of researches on osteoporosis pathomechanism, quality of life in patients, comorbidities, non-pharmacological methods for treatment of osteoporosis, the impact of physical exercise, role of diet as adjunctive therapy in osteoporosis were described.
Conclusions
Osteoporosis and treatment influence on the patient's functioning and subjective assessment of the quality of life. Medical doctors need to take into account high occurrence of multimorbidity in adults with osteoporosis to be able to propose comprehensive treatment. The treatment of the affected patients should be improved to offer early or even preventive care for other diseases that coexist with osteoporosis. Non-pharmacological interventions, such as diet, seem to be effective in osteoporosis. Effects of physical exercise could be beneficial in osteoporosis patients, however further studies are needed to determine specifics of the most effective program.

Keywords


osteoporosis; diet; physical exercise; resistance training

Full Text:

PDF

References


Khosla, S. (2010). Pathogenesis of osteoporosis. Translational endocrinology & metabolism, 1(1), 55.

Laurent, M., Gielen, E., Claessens, F., Boonen, S., & Vanderschueren, D. (2013). Osteoporosis in older men: recent advances in pathophysiology and treatment. Best practice & research Clinical endocrinology & metabolism, 27(4), 527-539.

Trajanoska, K., & Rivadeneira, F. (2019). The genetic architecture of osteoporosis and fracture risk. Bone, 126, 2-10.

Lizneva, D., Yuen, T., Sun, L., Kim, S. M., Atabiekov, I., Munshi, L. B., ... & Zaidi, M. (2018). Emerging concepts in the epidemiology, pathophysiology, and clinical care of osteoporosis across the menopausal transition. Matrix Biology, 71, 70-81.

Canalis, E., Mazziotti, G., Giustina, A., & Bilezikian, J. P. (2007). Glucocorticoid-induced osteoporosis: pathophysiology and therapy. Osteoporosis International, 18(10), 1319-1328.

Corley, D. A., Kubo, A. I., Zhao, W., & Quesenberry, C. (2010). Proton pump inhibitors and histamine-2 receptor antagonists are associated with hip fractures among at-risk patients. Gastroenterology, 139(1), 93-101.

Bazelier, M. T., De Vries, F., Vestergaard, P., Herings, R., Gallagher, A. M., Leufkens, H. G., & van Staa, T. P. (2013). Risk of fracture with thiazolidinediones: an individual patient data meta-analysis. Frontiers in endocrinology, 4, 11.

Carbone, L. D., Johnson, K. C., Robbins, J., Larson, J. C., Curb, J. D., Watson, K., ... & LaCroix, A. Z. (2010). Antiepileptic drug use, falls, fractures, and BMD in postmenopausal women: findings from the women's health initiative (WHI). Journal of Bone and Mineral Research, 25(4), 873-881.

Drezner, M. K. (2004). Treatment of anticonvulsant drug-induced bone disease. Epilepsy & Behavior, 5, 41-47.

Srivastava, R. K., Dar, H. Y., & Mishra, P. K. (2018). immunoporosis: immunology of Osteoporosis—Role of T Cells. Frontiers in immunology, 9, 657.

Faienza, M. F., Ventura, A., Marzano, F., & Cavallo, L. (2013). Postmenopausal osteoporosis: the role of immune system cells. Clinical and Developmental Immunology, 2013.

Perrini, S., Laviola, L., Carreira, M. C., Cignarelli, A., Natalicchio, A., & Giorgino, F. (2010). The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis. Journal of Endocrinology, 205(3), 201-210.

Dolzhenko, A. T., & Sagalovsky, S. (2016). Cellular and molecular mechanisms of osteoporosis: current concepts and future direction treatment. Современная ревматология, 10(2).

Neyro, B. J., Cano, S. A., & Palacios, G. A. S. (2011). Bone metabolism regulation through RANK-RANKL-OPG system. REVISTA DE OSTEOPOROSIS Y METABOLISMO MINERAL, 3(2), 105-112.

Group, W. H. O. Q. O. L. (1994). Development of the WHOQOL: Rationale and current status. International Journal of Mental Health, 23(3), 24-56.

Berzon, R., Hays, R. D., & Shumaker, S. A. (1993). International use, application and performance of health-related quality of life instruments. Quality of Life Research, 2(6), 367-368.

Lips, P., & van Schoor, N. M. (2005). Quality of life in patients with osteoporosis. Osteoporosis international, 16(5), 447-455.

Park, H. (2018). The impact of osteoporosis on health-related quality of life in elderly women. Biomedical Research, 29(16), 3223-3227.

Bjelica, A., Vučaj, Ć. V., Tomašević-Todorović, S., & Filipović, K. (2018). Postmenopausal osteoporosis. Medicinski pregled, 71(5-6), 201-205.

Tucker, L. A., Nokes, N. R., Bailey, B. W., & Lecheminant, J. D. (2014). Cardiorespiratory fitness and hip bone mineral density in women: A 6-year prospective study. Perceptual and motor skills, 119(2), 333-346.

Shah, N., Pandya, K., Gohil, D., & Seth, A. K. FACTORS, PREVENTION AND TREATMENT OF OSTEOPOROSIS: A.

DeFina, L. F., Leonard, D., Willis, B. L., Barlow, C. E., Finley, C. E., Jenkins, M. R., ... & Shen, C. L. (2016). High cardiorespiratory fitness is associated with reduced risk of low bone density in postmenopausal women. Journal of Women's Health, 25(10), 1073-1080.

Felsenberg, D., Silman, A. J., Lunt, M., Armbrecht, G., Ismail, A. A., Finn, J. D., ... & Bruges, J. A. (2002). Incidence of vertebral fracture in europe: results from the European Prospective Osteoporosis Study (EPOS). Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research, 17(4), 716-724.

Puth, M. T., Klaschik, M., Schmid, M., Weckbecker, K., & Münster, E. (2018). Prevalence and comorbidity of osteoporosis–a cross-sectional analysis on 10,660 adults aged 50 years and older in Germany. BMC musculoskeletal disorders, 19(1), 144.

Drosselmeyer, J., Rapp, M. A., Hadji, P., & Kostev, K. (2016). Depression risk in female patients with osteoporosis in primary care practices in Germany. Osteoporosis International, 27(9), 2739-2744.

Daly, R. M., Dalla Via, J., Duckham, R. L., Fraser, S. F., & Helge, E. W. (2018). Exercise for the prevention of osteoporosis in postmenopausal women: an evidence-based guide to the optimal prescription. Brazilian journal of physical therapy.

Tolomio, S., Ermolao, A., Lalli, A., & Zaccaria, M. (2010). The effect of a multicomponent dual-modality exercise program targeting osteoporosis on bone health status and physical function capacity of postmenopausal women. Journal of women & aging, 22(4), 241-254.

Tong, X., Chen, X., Zhang, S., Huang, M., Shen, X., Xu, J., & Zou, J. (2019). The Effect of Exercise on the Prevention of Osteoporosis and Bone Angiogenesis. BioMed research international, 2019.

Roghani, T., Torkaman, G., Movasseghe, S., Hedayati, M., Goosheh, B., & Bayat, N. (2013). Effects of short-term aerobic exercise with and without external loading on bone metabolism and balance in postmenopausal women with osteoporosis. Rheumatology international, 33(2), 291-298.

Gunendi, Z., Ozyemisci-Taskiran, O., & Demirsoy, N. (2008). The effect of 4-week aerobic exercise program on postural balance in postmenopausal women with osteoporosis. Rheumatology International, 28(12), 1217.

Taaffe, D. R., Daly, R. M., Suominen, H., Galvao, D. A., & Bolam, K. A. (2013). Physical activity and exercise in the maintenance of the adult skeleton and the prevention of osteoporotic fractures. In Osteoporosis (pp. 683-719). Academic Press.

Gianoudis, J., Bailey, C. A., Ebeling, P. R., Nowson, C. A., Sanders, K. M., Hill, K., & Daly, R. M. (2014). Effects of a targeted multimodal exercise program incorporating high‐speed power training on falls and fracture risk factors in older adults: a community‐based randomized controlled trial. Journal of bone and mineral research, 29(1), 182-191.

Madureira, M. M., Bonfá, E., Takayama, L., & Pereira, R. M. (2010). A 12-month randomized controlled trial of balance training in elderly women with osteoporosis: improvement of quality of life. Maturitas, 66(2), 206-211.

Czarkowska-Paczek, B., Wesołowska, K., & Przybylski, J. (2011). Physical exercise prevents osteoporosis. Przeglad lekarski, 68(2), 103-106.

Benedetti, M. G., Furlini, G., Zati, A., & Letizia Mauro, G. (2018). The effectiveness of physical exercise on bone density in osteoporotic patients. BioMed research international, 2018.

Zalińska, K., & Olszanowska, K. (2014). Nordic walking jako prewencja pierwotna i wtórna chorób cywilizacyjnych. Physiotherapy/Fizjoterapia, 22(1).

Grześkowiak, M., Leszczyński, P., & Lewandowski, J. (2013). Postêpowanie fizjoterapeutyczne u pacjentów z osteoporoz¹ bez z³amañ i ze z³amaniami. Menopausal Review/Przeglad Menopauzalny, 12(2).

Chow, T. H., Lee, B. Y., Ang, A. B. F., Cheung, V. Y. K., Ho, M. M. C., & Takemura, S. (2018). The effect of Chinese martial arts Tai Chi Chuan on prevention of osteoporosis: A systematic review. Journal of orthopaedic translation, 12, 74-84.

McMahon, M. (2017). What impact does aquatic therapy have on bone density in postmenopausal women? If it has a positive or maintenance effect, what are the programme parameters that facilitate these outcomes?. Aqualines: The Journal of the Hydrotherapy Association of Chartered Physiotherapists, 29(1).

Chan, G. M., Hoffman, K., & McMurry, M. (1995). Effects of dairy products on bone and body composition in pubertal girls. The Journal of pediatrics, 126(4), 551-556.

Nieves, J. W., Barrett-Connor, E., Siris, E. S., Zion, M., Barlas, S., & Chen, Y. T. (2008). Calcium and vitamin D intake influence bone mass, but not short-term fracture risk, in Caucasian postmenopausal women from the National Osteoporosis Risk Assessment (NORA) study. Osteoporosis International, 19(5), 673-679.

Szkop, I. (2001). Czynniki zywieniowe a metabolizm tkanki kostnej. Żywienie Człowieka i Metabolizm, 28(1), 71-85.

Billing-Marczak, K. (2008). Krotkiewski M.: Rola witaminy K w metabolizmie kości. Terapia, 209, 41-44.

Hugh L., Single M., Kishbaugh R.M., Buchwald M.: Skeletal system and joint health. W: Marian M.J., WilliamsMullen P., Bowers J.M. (red.).: Integrating therapeutic and complementary nutrition. Taylor and Francis, Nowy Jork 2007: 171–213.

Hall, S. L., & Greendale, G. A. (1998). The relation of dietary vitamin C intake to bone mineral density: results from the PEPI study. Calcified tissue international, 63(3), 183-189.

Bujko, J., & Bawa, S. (2006). Dietoterapia i dietoprofilaktyka osteoporozy. W: Bujko J.(red.).: Podstawy dietetyki. Wydawnictwo SGGW, Warszawa.




DOI: http://dx.doi.org/10.5281/zenodo.3386710

Refbacks

  • There are currently no refbacks.




Copyright (c) 2019 © The Author(s)

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)