Oral microbiota and systemic disease

Patrycja Łanowy, Miłosz Bichalski, Joanna Komasa, Katarzyna Mocny-Pachońska, Marta Tanasiewicz

Abstract


The oral cavity is has been resided by thousands of species of microorganisms, which remaining in different relationships. Disturbing the balance between microorganisms and host immunity can lead to the development of many serious local conditions, as well as changes in the organs placed away from the head and neck region. This article describes serious complications of local oral cavity infections like - exacerbation of chronic obstructive pulmonary, brain abscesses, infective endocarditis, diabetes mellitus, and even sepsis. The article also shows the potential connections between periodontal tissue inflammation and neurodegenerative disorders or cancer placed in distant organs. During treatment of periodontal patients, the physician should remember about the influence and risk of bacterial oral diseases.

Keywords


oral microbiota; systemic diseases; oral cavity health; diabetes; infective endocarditis; brain abscess

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References


Sampaio-Maia B, Caldas IM, Pereira ML, Pérez-Mongiovi D, Araujo R. The Oral Microbiome in Health and Its Implication in Oral and Systemic Diseases. Advances in Applied Microbiol. 2016;97;171-210.

Yangheng Z, Xiang W, Houxuan L, Can N, Zhibin D, et al. Human oral microbiota and its modulation for oral health. Biomedicine & Pharmacotherapy 2018;99;883-893.

Arweiler N.B, Netuschil L. The Oral Microbiota. Adv Exp Med Biol. 2016;902;45-60.

Le PT, Hamasuna R, Matsumoto M, Furubayashi K, Hatanaka M, et al.The detection of microorganisms related to urethritis from the oral cavity of male patients with urethritis. J Infect Chemother. 2017;23(10);668-673.

Hajishengallis G. Periodontitis: from microbial immune subversion to systemic inflammation. Nat Rev Immunol. 2015;15(1);30–44.

Peterson SN, Meissner T, Su AI, Snesrud E, Ong AC,, et al. Functional expression of dental plaque microbiota. Front Cell Infect Microbiol. 2014;4;108

Angelino K, Shah P, Edlund DA, Mohit M, Yauney G. Clinical validation and assessment of a modular fluorescent imaging system and algorithm for rapid detection and quantification of dental plaque. BMC Oral Health. 2017;17(1);162.

Huang X, Browngardt CM, Jiang M, Ahn SJ, Burne RA, et al. Diversity in Antagonistic Interactions between Commensal Oral Streptococci and Streptococcus mutans. Caries Res. 2018;52(1-2);88–101.

Sreenivasan PK, Prasad KVV. Distribution of dental plaque and gingivitis within the dental arches. J Int Med Res. 2017;45(5);1585–1596.

Peterson SN, Snesrud E, Liu J, Ong AC, Kilian M, et al. The dental plaque microbiome in health and disease. PLoS One. 2013;8(3);584-587.

Hajishengallis G. Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response. Trends Immunol. 2014;35(1);3–11.

Huang TT, Liu TC, Chen PR, Tseng FY, Yeh TH,et al. Deep neck infection: analysis of 185 cases. Head Neck. 2004; 26(10);854–860.

Cardoso Abel S., Mitchell David F. 1971 Progression of Pulpitis to Necrosis and Periapical Disease in Deciduous and Permanent Teeth of Monkeys. J Dent Res. 1971;50(4);934–938.

Hubert N. Newman. Focal Infection. J Dent Res. 1996;75(12);1912–1919.

Ko HH, Chien WC, Lin YH, Chung CH, Cheng SJ. Examining the correlation between diabetes and odontogenic infection: A nationwide, retrospective, matched-cohort study in Taiwan. PLoS One. 2017;12(6);e0178941.

Rai K, Hegde AM, Kamath A, Shetty S. Dental caries and salivary alterations in Type I Diabetes. J Clin Pediatr Dent. 2011;36(2);181-4.

Seethalakshmi C, Jagat Reddy RC, Asifa N, Prabhu S. Correlation of Salivary pH, Incidence of Dental Caries and Periodontal Status in Diabetes Mellitus Patients: A Cross-sectional Study. J Clin Diagn Res. 2016 Mar;10(3);ZC12–ZC14.

Segura-Egea JJ, Castellanos-Cosano L, Machuca G, et al. Diabetes mellitus, periapical inflammation and endodontic treatment outcome. Med Oral Patol Oral Cir Bucal. 2011;17(2);356–361.

Delamaire M, Maugendre D, Moreno M, Le Goff MC, Allannic H, et al. Impaired leucocyte functions in diabetic patients. Diabet Med. 1997Jan;14(1);29-34.

Lacopino AM. Periodontitis and diabetes interrelationships: role of inflammation. Ann Periodontol. 2001;6;125–137.

Salvi GE, Carollo-Bittel B, Lang NP. Effects of diabetes mellitus on periodontal and peri-implant conditions: update on associations and risks. J Clin Periodontol. 2008;35(8);398–409.

Ueta E, Osaki T, Yoneda K, Yamamoto T. Prevalence of diabetes mellitus in odontogenic infections and oral candidiasis: an analysis of neutrophil suppression. J Oral pathol & Med. 1993;22;168-74.

Zahedi L, Jafari E, Torabi Parizi M, et al. The Association between Oral Hygiene and Gastric Pathology in Patients with Dyspepsia: a Cross-Sectional Study in Southeast Iran. Middle East J Dig Dis. 2017;9(1);33–38.

Haumschild MS, Haumschild RJ. The Importance of Oral Health in Long-Term Care. J Am Med Dir Assoc. 2009;10:667-71.

Loster BW, Majewski SW, Cześnikiewicz-Guzik M, Bielanski W, Pierzchalski P, Konturek SJ. The relationship between the presence of Helicobacter pylori in the oral cavity and gastric in the stomach. J Physiol Pharmacol. 2006;57;91-100.

Cześnikiewicz-Guzik M, Karczewska E, Bielański W, Guzik TJ, Kapera P, et al. Association of the presence of Helicobacter pylori in the oral cavity and in the stomach. J Physiol Pharmacol. 2004;55;105-15.

Banić M, Buljevac M, Kujundzić M, Jelić D, Dominis M, et al. Extra-gastrointestinal tract diseases and Helicobacter pylori infection. Lijec Vjesn. 2002;124;63-8.

Piekoszewska-Ziętek P, Turska-Szybka A, Olczak-Kowalczyk D. Odontogenic infections – review of the literature. Borgis - New Stomatology 2016;2;120-134.

Li X, Kolltveit KM, Tronstad L, Olsen I: Systemic diseases caused by oral infection. Clin Microbiol Rev. 2000;13(4);547-558.

Waites KB, Xiao L, Liu Y, Balish MF, Atkinson TP. Mycoplasma pneumoniae from the Respiratory Tract and Beyond. Clin Microbiol Rev. 2017;30(3);747–809.

Hagiwara, Shin-ichiro et al. Lung abscess caused by infection of Actinobacillus actinomycetemcomitans. Pediatrics international : official journal of the Japan Pediatric Society 515. 2009;748-51 .

Shilo S, Kassis I, Hakim F, Shachor-Meyouhas Y. Aggregatibacter actinomycemcomitans pneumonia in children: two case reports and a review of the literature. Pediatr Infect Dis J. 2015;34(1);100-2.

Endo S, Mishima E, Takeuchi Y, et al. Periodontitis-associated septic pulmonary embolism caused by Actinomyces species identified by anaerobic culture of bronchoalveolar lavage fluid: a case report. BMC Infect Dis. 2015;15;552.

Scannapieco FA. Individuals with chronic obstructive pulmonary disease (COPD) may be more likely to have more severe periodontal disease than individuals without COPD. J Evid Based Dent Pract. 2014;14(2);79-81.

Peter KP, Mute BR, Doiphode SS, Bardapurkar SJ, Borkar MS,et al. Association between periodontal disease and chronic obstructive pulmonary disease: a reality or just a dogma? J Periodontol. 2013;84(12);1717-23.

Cannon CL, Kowalski MP, Stopak KS, Pier GB. Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator. Am J Respir Cell Mol Biol. 2003;29(2);188-97.

Brady P, Bergin S, Cryan B, Flanagan O. Intracranial abscess secondary to dental infection. J Ir Dent Assoc. 2014;60(1);32-4.

Kamer AR, Craig RG, Dasanayake AP, Brys M, Glodzik-Sobanska L, et al. Inflammation and Alzheimer's disease: possible role of periodontal diseases. Alzheimers Dement. 2008;4(4);242-50.

Sparks Stein P, Steffen MJ, Smith C, Jicha G, Ebersole JL, et al. Serum antibodies to periodontal pathogens are a risk factor for Alzheimer's disease. Alzheimers Dement. 2012;8(3);196–203.

Watts A, Crimmins EM, Gatz M. Inflammation as a potential mediator for the association between periodontal disease and Alzheimer's disease. Neuropsychiatr Dis Treat. 2008;4(5);865–876.

Chen CK, Wu YT, Chang YC. Periodontal inflammatory disease is associated with the risk of Parkinson's disease: a population-based retrospective matched-cohort study. PeerJ. 2017;5;3647.

Kaur T, Uppoor A, Naik D. Parkinson's disease and periodontitis - the missing link? A review. Gerodontology. 2016; 33(4);434-438.

Chen CK, Huang JY, Wu YT, Chang YC. Dental Scaling Decreases the Risk of Parkinson's Disease: A Nationwide Population-Based Nested Case-Control Study. Int J Environ Res Public Health. 2018;15(8);1587.

Akashi M, Tanaka K, Kusumoto J, Furudoi S, Hosoda K, et al. Brain Abscess Potentially Resulting from Odontogenic Focus: Report of Three Cases and a Literature Review. J Maxillofac Oral Surg. 2017;16(1);58–64.

Ranjan R, Abhinay A, Mishra M. Can oral microbial infections be a risk factor for neurodegeneration? A review of the literature. Neurol India. 2018;66;344-51.

Ben Hadj Hassine M, Oualha L, Derbel A, Douki N. Cerebral abscess potentially of odontogenic origin. Case Rep Dent. 2015; 2015;267625.

Tupchong K, Koyfman A, Foran M. Sepsis, severe sepsis, and septic shock: A review of the literature. African Journal of Emergency Medicine. 2015;5(3);127-135.

Stearns-Kurosawa DJ, Osuchowski MF, Valentine C, Kurosawa S, Remick DG. The pathogenesis of sepsis. Annu Rev Pathol. 2011;6;19–48.

Van Amersfoort ES, Van Berkel TJC, Kuiper J. Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock. Clinical Microbiology. 2003;16(3);379-414.

Van der Windt D, Kornegoor R, Walhof R, Overbeek BP, Paarlberg KM. Septicaemia with Fusobacterium necrophorum from Periodontal Disease in Pregnancy Resulting in Immature Birth: Case Report and Review of Literature. Obstet Gynecol Cases Rev. 2018;5;116.

Gupta M, Annam R, Bahgat J, Eng M. Porphyromonas asaccharolytica as a Rare Causative Agent for Lemierre’s Syndrome. Case Rep Infect Dis. 2018.

Eilbert W, Singla N. Lemierre's syndrome. Int J Emerg Med. 2013;6(1);40.

Garza-Alatorre A, Hernández-Rosales C, Rodríguez-Coronado J, Solís-González MC, Balderrama-Dávila R, et al. Atypical Lemierre’s syndrome caused by Prevotella oris. Medicina universitaria. 2015;17(69);218–221.

Terai T, Okumura T, Imai S, Nakao M, Yamaji K, et al. Screening of Probiotic Candidates in Human Oral Bacteria for the Prevention of Dental Disease. PLoS One. 2015 Jun 8;10(6);e0128657.

Muñoz P, Kestler M, De Alarcon A, Miro JM, Bermejo J, et al. Current Epidemiology and Outcome of Infective Endocarditis: A Multicenter, Prospective, Cohort Study. Medicine (Baltimore). 2015 Oct;94(43);1816.

Duval X, Millot S, Chirouze C, Selton-Suty C, Moby V, Tattevin P, et al. Oral Streptococcal Endocarditis, Oral Hygiene Habits, and Recent Dental Procedures: A Case-Control Study. Clin Infect Dis. 2017;64(12);1678–1685.

Holland TL, Baddour LM, Bayer AS, Hoen B, Miro JM, et al. Infective endocarditis. Nat Rev Dis Primers. 2016;2.

Mang-de la Rosa MR, Castellanos-Cosano L, Romero-Perez MJ, Cutando A. The bacteremia of dental origin and its implications in the appearance of bacterial endocarditis. Med Oral Patol Oral Cir Bucal. 2013;19(1);67–74.

Whatling PJ, Robb JD, Byrne J, Wendler O. Can we really do without antibiotic prophylaxis for infective endocarditis?. BMJ Case Rep. 2011.

Ohara-Nemoto Y, Kishi K, Satho M, Tajika S, Sasaki M, et al. Infective endocarditis caused by Granulicatella elegans originating in the oral cavity. J Clin Microbiol. 2005;43(3);1405–1407.

Kim GW, Kim YS, Lee SH, Park SG, Kim DH, et al. Periodontitis is associated with an increased risk for proximal colorectal neoplasms. Sci Rep. 2019;9(1)..

Hoare A, Soto C, Rojas-Celis V, Bravo D. Chronic Inflammation as a Link between Periodontitis and Carcinogenesis. Mediators Inflamm. 2019;2019;1029857.

Corbella S, Veronesi P, Galimberti V, Weinstein R, Del Fabbro M,et al. Is periodontitis a risk indicator for cancer? A meta-analysis. PLoS One. 2018;13(4).

Michaud DS, Lu J, Peacock-Villada AY, Barber JR, Joshu CE, et al. Periodontal Disease Assessed Using Clinical Dental Measurements and Cancer Risk in the ARIC Study. J Natl Cancer Inst. 110(8);843–854.

Hashim D, Sartori S, Brennan P, Curado MP, Wünsch-Filho V, et al. The role of oral hygiene in head and neck cancer: results from International Head and Neck Cancer Epidemiology (INHANCE) consortium. Ann Oncol. 2016;27(8);1619–1625.

Arunkumar KV. Orbital Infection Threatening Blindness Due to Carious Primary Molars: An Interesting Case Report. J Maxillofac Oral Surg. 2016;15(1):72-5.

Gordon MO, Torri V, Miglior S, Beiser JA, Floriani I. Validated prediction model for the development of primary open-angle glaucoma in individuals with ocular hypertension. Ophthalmology. 2007;114;10–19.

Stasi K, Nagel D, Yang X, Wang RF, Ren L. Complement component 1Q (C1Q) upregulation in retina of murine, primate, and human glaucomatous eyes. Invest Ophthalmol Vis. 2006;47:1024–1029.

Bosco A, Steele MR, Vetter ML. Early microglia activation in a mouse model of chronic glaucoma. J Comp Neurol. 2011;519:599–620.

Astafurov K, Elhawy E, Ren L, Dong CQ, Igboin C, et al. Oral microbiome link to neurodegeneration in glaucoma. PloS One. 2014;9(9);e104416.

Ni YQ, Xu GZ, Hu WZ, Shi L, Qin YW, et al. Neuroprotective effects of naloxone against light-induced photoreceptor degeneration through inhibiting retinal microglial activation. Invest Ophthalmol Vis Sc. 2008;49;2589–2598.

Hunsigi P, Kumar V, Pradeep MR, Arun Kumar BC. Knowledge and Attitude of Dental Surgeons about Ocular Complications Due to Dental Infection. J Pharm Bioallied Sci. 2017;9:147-153.

Youssef OH, Stefanyszyn MA, Bilyk JR. Odontogenic orbital cellulitis. Ophthalmic Plast Reconstr Surg. 2008;24(1):29-35.

Park CH, Jee DH, La TY. A case of odontogenic orbital cellulitis causing blindness by severe tension orbit. J Korean Med Sci. 2013;28(2):340-3.

DeCroos FC, Liao JC, Ramey NA, Li I. Management of odontogenic orbital cellulitis. J Med Life. 2011;4(3):314-7.

Srinivasa Prasad B, Govardhan T. A rare case of orbital cellulitis followed by therapeutic(orthodontic) extraction. J Maxillofac Oral Surg. 201;10(3):257-61.

Arora N, Juneja R, Meher R. Complication of an Odontogenic Infection to an Orbital Abscess: The Role of a Medical Fraudster ("Quack"). Iran J Otorhinolaryngol. 2018;30(98):181-184.




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