Relationships between the entropies of EEG, HRV, immunocytogram and leukocytogram

O Popadynets’, A Gozhenko, W Zukow, I Popovych

Abstract


Background. In mathematics the entropy is a measure of uncertainty of a random function; in the theory of information entropy is a measure of uncertainty in a situation, any experience (test) that can have different consequences. The entropy is also a measure of disorder, the degree of chaos present in the system. CE Shannon linked the mathematical dependence of the concept of information and entropy, which characterizes the degree of ordering of the system. This estimate of the amount of information coincides with the estimation of the quantitative measure of elimination of uncertainty of entropy, the degree of organization of the system. It is well known about functional interactions between central and autonomic nervous and immune systems. In the context of this concept, we have prioritized research on the interconnections between the entropies of these systems. Material and methods. In basal conditions in 37 men and 14 women with chronic pyelonephritis and cholecystitis in remission as well as without clinical diagnose but with dysfunction of neuro-endocrine-immune complex and metabolism, we recorded twice, before and after balneotherapy at the spa Truskavets’, EEG (“NeuroCom Standard”) and HRV (“Cardiolab+VSR”). In blood we determined relative content of components (RCC) of Immunocytogram (ICG) (T helper, T cytolytic, B and NK lymphocytes) and Leukocytogram (LCG) (Eosinophils, Stub and Segmentonucleary Neutrophils, Lymphocytes and Monocytes). Than we calculated for each locus of EEG and HRV as well as for ICG and LCG the Entropy (h) of normalized spectral power density (SPD) or RCC using Shannon’s formula: Results. There was a complete absence of correlation between hHRV and hLCG (r=-0,03) as well as hICG (r=-0,03), whereas the relationship between hLCG and hICG is significant (r=-0,40; p<0,001). Accepting the entropy of EEG HRV as a factor, using the correlation analysis with step-by-step exclusion, we obtain the equations for dependent variables. Canonical correlation between hHRV&EEG, on the one hand, and hLCG&Immunity, on the other hand, is strong: R=0,814; R2=0,663; χ2(240)=296; p=0,008. Conclusion. The enropy of HRV and EEG significantly correlate with the entropy and parameters of immunity, which testifies to their modulating regulatory effects.

Keywords


EEG; HRV; Leukocytogram, Immunocytogram; Entropy; Correlations; Women and Man.

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References


Avtandilov GG. Medical Morphometry [in Russian]. Moskva. Meditsina; 1990: 384 p.

Baevskiy RM, Ivanov GG. Heart Rate Variability: theoretical aspects and possibilities of clinical application [in Russian]. Ultrazvukovaya i funktsionalnaya diagnostika. 2001; 3: 106-127.

Barylyak LG., Malyuchkova RV, Tolstanov OB, Tymochko OB, Hryvnak RF, Uhryn MR. Comparative estimation of informativeness of leukocytary index of adaptation by Garkavi and by Popovych. Medical Hydrology and Rehabilitation. 2013; 11(1): 5-20.

Berntson GG, Bigger JT jr, Eckberg DL, Grossman P, Kaufman PG, Malik M, Nagaraja HN, Porges SW, Saul JP, Stone PH, Van der Molen MW. Heart Rate Variability: Origines, methods, and interpretive caveats. Psychophysiology. 1997; 34: 623-648.

Biloshytskyi PV. Temperature, Information, Water, Anabiosis, Immortality [in Ukrainian]. Health and Longevity. Kyiv; 2007: 46-47.

Biloshytskyi PV, Biloshytskyi SP, Klyuchko OM. Conceptual Foundations of Bioinformation [in Ukrainian]. Cosmos and the Biosphere. Partenit; 2005: 131-132.

Dranovs’kyi AL, Popovych IL. Adaptogenic Balneotherapy on Spa Truskavets’ [in Ukrainian]. Drohobych. Posvit; 2010: 203 p.

Douglas SD, Quie PG. Investigation of Phagocytes in Disease. Churchil; 1981: 110 p.

Garkavi LKh, Kvakina EB, Ukolova MA. Adaptation Reactions and Resistance of Organism [in Russian]. Rostov na Donu. Publishing House of Rostov University Press, 3rd ed; 1990: 224 p.

Garkavi LKh, Kvakina EB, Kuz’menko TS. Antistressory Reactions and Activating Therapy [in Russian]. Moskva. Imedis; 1998: 654 p.

Garkavi LKh, Romasyuk SI, Barantsev FG, Kuz’menko TS, Otkidach SA, Tatkov OV, Barantseva LP. Activation therapy in the complex of the sanatorium-resort stage of rehabilitation of patients with diseases of internal organs [in Russian]. Sochi; 2000: 94 p.

Heart Rate Variability. Standards of Measurement, Physiological Interpretation, and Clinical Use. Task Force of ESC and NASPE. Circulation. 1996; 93(5): 1043-1065.

Kostyuk PG, Popovych IL, Іvassivka SV (editors). Chornobyl’, Adaptive and Defensive Systems, Rehabilitation [in Ukrainian]. Kyiv. Computerpress; 2006: 348 p.

Kul’chyns’kyi AB, Gozhenko AI, Popovych IL. Interrelations between autonomous and immune systems (review) [in Ukrainian]. Actual problems of transport medicine. 2017; 3(49): 7-25.

Kul’chyns’kyi AB, Gozhenko AI, Zukow W, Popovych IL. Neuro-immune relationships at patients with chronic pyelonephrite and cholecystite. Communication 3. Correlations between parameters EEG, HRV and Immunogram. Journal of Education, Health and Sport. 2017; 7(3): 53-71.

Kul’chyns’kyi AB, Kovbasnyuk MM, Korolyshyn TA, Kyjenko VM, Zukow W, Popovych IL. Neuro-immune relationships at patients with chronic pyelonephrite and cholecystite. Communication 2. Correlations between parameters EEG, HRV and Phagocytosis. Journal of Education, Health and Sport. 2016; 6(10): 377-401.

Kul’chyns’kyi AB, Kyjenko VM, Zukow W, Popovych IL. Causal neuro-immune relationships at patients with chronic pyelonephritis and cholecystitis. Correlations between parameters EEG, HRV and white blood cell count. Open Medicine. 2017; 12(1): 201-213.

Lapovets’ LYe, Lutsyk BD. Handbook of Laboratory Immunology [in Ukrainian]. Lviv. 2002. 173 p.

Newberg AB, Alavi A, Baime M, Pourdehnad M, Santanna J, d’Aquili E. The measurement of regional cerebral blood flow during the complex cognitive task of meditation: a preliminary SPECT study. Psychiatry Research: Neuroimaging Section. 2001; 106: 113-122.

Petsyukh SV, Petsyukh MS, Kovbasnyuk MM, Barylyak LG, Zukow W. Relationships between Popovych’s Adaptation Index and parameters of ongoiging HRV and EEG in patients with chronic pyelonephrite and cholecystite in remission. Journal of Education, Health and Sport. 2016; 6(2): 99-110.

Popovych IL (editor). General Adaptation Reactions and Body's Resistance in Liquidators of the Chernobyl Accident [in Ukrainian]. Kyiv. Computerpress; 2000: 117 p.

Popоvych IL. Information effects of bioactive water Naftyssya in rats: modulation entropic, prevention desynchronizing and limitation of disharmonizing actions water immersion stress for information components of neuro-endocrine-immune system and metabolism, which correlates with gastroprotective effect [in Ukrainian]. Medical Hydrology and Rehabilitation. 2007; 5(3): 50-70.

Popovych IL, Kozyavkina OV, Kozyavkina NV, Korolyshyn TA, Lukovych YuS, Barylyak LG. Correlation between Indices of the Heart Rate Variability and Parameters of Ongoing EEG in Patients Suffering from Chronic Renal Pathology. Neurophysiology. 2014; 46(2): 139-148.

Popovych IL, Lukovych YuS, Korolyshyn TA, Barylyak LG, Kovalska LB, Zukow W. Relationship between the parameters heart rate variability and background EEG activity in healthy men. Journal of Health Sciences. 2013; 3(4): 217-240.

Radchenko OM. Adaptation Reactions in Internal Diseases Clinic [in Ukrainian]. Lviv: League-Press. 2004. 232 p.

Romodanov AP (editor). Postradiation Encephalopathy. Experimental Researches and Clinical Observations [in Ukrainian and Russian]. Kyiv. USRI of Neurosurgery; 1993: 224 p.

Shannon CE. Works on the theory of informatics and cybernetics [transl. from English to Russian]. Moskwa: Inostrannaya literatura; 1963: 329 p.

Tracey K.J. Physiology and immunology of the cholinergic antiinflammatory pathway. J Clin Invest. 2007; 117(2): 289-296.

Yushkovs’ka OG. Using information theory to study adaptive responses in the body athletes [in Ukrainian]. Medical Rehabilitation, Kurortology, Physiotherapy. 2001; 1(25): 40-43.




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