Results of the treatment of the patients with malignant fibro histiocytoma of low limbs soft tissues

O. O. Litvinenko, S. I. Korovin, L. B. Kutsenko


The basis of the research was the analysis of the results of treatment of 130 patients with malignant fibrous histiocytoma of limbs soft tissues. The patients were treated at the National Cancer Institute from 1985 to 2016. The analysis made showed that the overall survival rate of the patients under examination depends on the location of the primary tumor. Indicators of recurrence-free survival differ significantly depending on the localization of the tumor. In relapsing patients overall survival is different and depends on the method of treatment. In the course of the first six years, the indicators of overall survival are better in the patients underwent only surgical treatment. The overall survival rate for all patients with MFH depends on the treatment method.


malignant fibrous histiocytoma of soft tissues; general survival; recurrent-free survival; surgical; combined; and complex treatment

Full Text:



Aliev MD (2004) Modern approaches to the treatment of soft tissue sarcomas. Practical Oncology, 5 (4): 250-255.

Shapiro NA., Patoroev YuK., Kislitsina LYu. (2009) Cytological diagnosis of soft tissue tumors. Atlas. - M. - Irkutsk, 5: 216.

Sekhina OV, Fedyanin M.Yu., Yakovleva E.S., Bulanov AA, Bokhyan B.Yu. (2011) Malignant fibrous histiocytomas. The results of the combined treatment of resectable forms. Sarcomas of bones, soft tissues and skin tumors, 4: 37-40.

Bolgova LS., Alekseenko OI., Loginova EA., Krotevich MS. (2014). Features of differential cytological diagnosis of malignant fibrous histiocytoma. Oncology.16 (3): 177-180.

Pobirci D.D., Bogdan F, Pobirci О.,et. al. (2011). Study of malignant fibrous histiocytoma: clinical, statistic and histopatological interrelation. Rom. J. Morphol. Embryol, 52(1 Suppl): 385-388.

Mankin HJ., Hornicek FJ., Delaney TF. [] (2012). Pleomorphic spindle cell sarcoma (PSCS) formerly known as malignant fibrous histiocytoma (MFH); a complex malignant soft-tissue tumor. Musculoskelet. Surg. 96(3): 171-177.

Milov VE. (2005). Treatment of patients with malignant fibrous histiocytoma (ZFG) of soft tissues and prognostic factors. Author's abstract dis. Cand. honey. sciences. - M., 22 p.

Aliev MD, Bohyan B.Yu., Burov D.A. (2013). The prognostic role of the resection margin in surgery of soft tissue sarcomas. Pract. Oncol 14: 97-100.

Pezzi CM., Rawlings MS., Esgro JJ., Pollock RE., Romsdahl MM. (1992). Prognostic factors in 227 patients with malignant fibrous histiocytoma. Cancer. 69(8): 2098-2103.

Fagundes HM., Lai PP., Detainer LP., Perez CA., Garcia DM., Emami BF., Simpson JR., Kraybill WG., Kucik NA. (1992) Postoperative radiotherapy for malignant fibrous histiocytoma. Int. J. Radiat. Oncol. Biol. Phys. – 23(3): 615-619.

Belal A., Kandil A., Allam A. et. al. (2002) Malignant fibrous histiocytoma; a retrospective study of 109 cases. Am. J. clin. Oncol, 25(1): 16-22.

Chitturi RT., Nirmal RM., Sunil P M. et al. (2014). Evaluation of ploidy status using DNA-image cytometry of exfoliated mucosal cells in oral lichen planus. J. Cytol. 31 (3): 131-135.

Sekhina OV., Fedyanin MYu., Yakovleva ES., Bulanov AA., Bokhyan B Yu. (2011) Malignant fibrous histiocytomas. Results of the combined treatment of resectable sarcoma of bones, soft tissues and skin tumors, 4: 37-40.

Korovin SI, Ivankova VS., Ostafiychuk VV., Palivetz AYu., Kukushkina MM., Kostiuk VYu., Krotevich MS., Paliy MI. (2016) Immediate results of neoadjuvant therapy in patients with high risk sarcoma of soft tissues. Clinical Oncology, 1 (21): 16-18.

Cormier JN., Pollock RE. (2004). Soft tissue sarcomas. J. Clin. Oncol, 54(2): 94-109.

Ferguson PC. (2005). Surgical considerations for management of distal extremity soft tissue sarcomas. Curr. Opin. Oncol.,17: 366-369.

Eilber FC., Dry SM. (2008) Diagnosis and management of synovial sarcoma. J. Surg. Oncol., 97: 314-320.

Weitz J., Antonescu CR., Brennan MF. (2003) Localized extremity soft tissue sarcoma improved knowledge with unchanged survival over time. J. Clin. Oncol., 21: 2719-2725.

Aliyev, MD, Mehdiyeva, NI, Bokhyan, B. Yu. (2005). Factors of prognosis of soft tissue sarcomas. Questions of Oncology, 51 (3): 288-291.

Korovin SI, Ivankova VS, Ostafiychuk V.V., Palivets A.Yu., Kukushkina M. M., Paliy M.I. (2015). Combined treatment for patients with sarcoma of soft tissues of the limbs and trunk. Clinical Oncology, 3 (19): 32-35.

Koea JB., Leung D., Lewis J., et al. (2003). Histopathologic type: An independent prognostic factor in primary soft tissue sarcoma of the extremity. Ann. Surg. Oncol., 10 (4): 432 - 440.



  • There are currently no refbacks.

Copyright (c) 2019 © The Author (s) 2019

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

POL-index 2011 - 2014

BASE 2011 - 2014

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

Find a library that holds this journal:

Journal Language(s): English 

PBN Poland



Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2 Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase


Universal Impact Factor 1.78 for year 2012. (

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ)

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski