The role of probiotics in the process of improvement of patients after arterial repair operations

Agnieszka Wilczyńska, Katarzyna Korabiusz, Agata Wawryków, Martyna Maciejewska, Monika Stecko, Anna Fabian-Danielewska, Inga Janik-Fuks


This paper aims to is to review the literature on the relationship between microbiota and the immune system in terms of the quality of life of patients after arterial repair operations. Angiology is a branch of medicine dealing with vascular diseases of the blood and lymphatic system. As a sub-discipline of surgery, together with techniques of surgical radiology, it has gained high recognition in the medical environment. Despite increasing progress in the process of arterial repair, postoperative complications in the form of swelling of the lower extremities of the operated side are still a problem. This problem concerns about 6% of patients. Another problem is the risk of vascular transplant infection. The high mortality rate estimated at 9% is worrying. Equally alarming is the percentage of limb amputations at the level of the shin or thigh. It should also be emphasized that the above complications may significantly indicate weakened immunity of patients, thus translating into the slower tissue regeneration process. Even the increasing degree of emotional disturbances as a result of weakened microflora.


angiology; immunology; lymphatic system; probiotic therapy; microbiota; dysbiosis; intestinal barrier; irritable bowel syndrome; rehabilitation; kinesitherapy; quality of life.

Full Text:



Walter Cromer, Ph.D., Wei Wang, M.D., Scott D. Zawieja, B.S., Pierre-Yves von der Weid, Ph.D., M. Karen Newell Rogers, Ph.D., and David C. Zawieja, Ph.D. Department of Medical Physiology, Division of Lymphatic Biology, Texas A&M University Health Science Center College of Medicine, Temple TX USA 76504: Colonic insult impairs lymph flow, increases cellular content of the lymph, alters local lymphatic micro-environment and leads to sustained inflammation in the rat ileum.

Jeremiah Bernier-Latmani and Tatiana V. Petrova :Intestinal lymphatic vasculature: structure, mechanisms and functions

Gwendalyn J. Randolph1, Stoyan Ivanov1, Bernd H. Zinselmeyer1 i Joshua P. Washington University School of Medicine, St. Louis, Missouri 631102 University of South Florida, Tampa, Floryda 33612.:The Lymphatic System: Integral Roles in Immunity

Marlicz W., Łoniewski I., GrimesDS., i wsp. Nonsteroidal anti-inflammatory drugs, proton pump inhibitors and gastrointestinal injury: contrasting interactions in the stomach and small intestine. Mayo Clin Proc. 2014;89:1699-709

Marlicz W., Starzyńska T., Marlicz K.: Pacjent z zespołem jelita nadwrażliwego w praktyce lekarza gastroenterologa. Polska 2013; 20: 61-68

Marlicz W. Wysiłek fizyczny a mikroflora przewodu pokarmowego- znaczenie probiotyków w diecie sportowców. Forum Zaburzenia Metaboliczne. 2014;5:129-140

Surgical wound infections after peripheral vascular surgery. Scand J Surg. 2014 Dec;103(4):226-31. doi: 10.1177/1457496913514384. Epub 2014 Apr 15.

Erb S., Sidler JA, Elzi L., Gurke L., Battegay M., Widmer AF, Weisser M. Surgical and antimicrobial treatment of prosthetic vascular graft infections at different surgical sites: a retrospective study of treatment outcomes. PLoSOne. 2014;

Turtiainen J., Hakala T., Hakkarainen T., Karhukorpi J. The impact of surgical wound bacterial colonization on the incidence of surgical site infection after lower limb vascular surgery: a prospective observational study. Eur. J. Vasc. Endovasc.


Liu SJ, Yin CX, Ding MC, Wang YZ Distribution and dtug resistance of pathogens causing surgical incision infections in vascular surgery department. Chinese Journal of Nosocomiology.2014; 24 (17):4295–4297

Neumayer L., Hosokawa P., Itani K., El-Tamer M., Henderson WG, Khuri SF Multivariable predictors of postoperative surgical site infection after general and vascular surgery: results from the patient safety in surgery study.J. Am. Coll. Surg. 2007; 204(6):1178–1187

Yong-Gan Zhang, Xue-Li Guo, Yan Song, Chao-Feng Miao, Chuang Zhang, and Ning-Heng Chen: Diagnosis and Treatment of Vascular Surgery Related Infection, Received 2015 May 26; Revised 2015 Jul 14; Accepted 2015 Aug 10.

Dethlefsen, L., Huse, S., Sogin, M. L. & Relman, D. A. The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PLoS Biol. 6, e280 (2008).

Frei E, Hodgkiss-Harlow K, Rossi PJ, Edmiston CE Jr.: Microbial pathogenesis of bacterial biofilms: a causative factor of vascular surgical site infection DF.Vasc Endovascular Surg. 2011 Nov;45(8):68896.doi:10.1177/1538574411419528.

Craig M Walker, Frank T Bunch, Nick G Cavros, Eric J Dippel: Multidisciplinary approach to the diagnosis and management of patients with peripheral arterial disease, Clin Interv Aging. 2015; 10: 1147–1153. Published online 2015 Jul 10. doi:10.2147/CIA.S79355

Conte MS, Bradbury AW, Kolh P, White JV, Dick F, Fitridge R, Mills JL, Ricco JB, Suresh KR, Murad MH; GVG Writing Group, Aboyans V, Aksoy M, Alexandrescu VA, Armstrong D, Azuma N, Belch J, Bergoeing M, Bjorck M, Chakfé N, Cheng S, Dawson J, Debus ES, Dueck A, Duval S, Eckstein HH, Ferraresi R, Gambhir R, Garguilo M, Geraghty P, Goode S, Gray B, Guo W, Gupta PC, Hinchliffe R, Jetty P, Komori K, Lavery L, Liang W, Lookstein R, Menard M, Misra S, Miyata T, Moneta G, Prado JAM, Munoz A, Paolini JE, Patel M, Pomposelli F, Powell R, Robless P, Rogers L, Schanzer A, Schneider P, Taylor S, Vega De Ceniga M, Veller M, Vermassen F, Wang J, Wang S; Global vascular guidelines on the management of chronic limb-threatening ischemia.

Joint guidelines of the Society for Vascular Surgery; European Society for Vascular Surgery; World Federation of Vascular Societies.

J Vasc Surg. 2019 Jun;69(6S):3S-125S.e40. doi: 10.1016/j.jvs.2019.02.016. Epub 2019 May 28. PMID:31159978

Ashkan Farhadi: Intestinal barrier: An interface between health and disease. Journal of Gastroenterology and Hepatology,15 April 2003

Walter Cromer, Ph.D., Wei Wang, M.D., Scott D. Zawieja, B.S., Pierre-Yves von der Weid, Ph.D., M. Karen Newell Rogers, Ph.D., and David C. Zawieja, Ph.D.:Colonic insult impairs lymph flow, increases cellular content of the lymph, alters local lymphatic micro-environment and leads to sustained inflammation in the rat ileum. Inflamm Bowel Dis. 2015 July ; 21(7): 1553–1563. doi:10.1097/MIB.0000000000000402.

Suh J.W., Ju Y., Lee CK., Sohn JW, Kim MJ, Yoon YK.: Molecular epidemiology and clinical significance of Corynebacterium striatum isolated from clinical specimens. Jan 4;12:161-171. doi: 10.2147/IDR.S184518. e Collection 2019



  • There are currently no refbacks.

Copyright (c) 2019 © The Author(s)

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

POL-index 2011 - 2014

BASE 2011 - 2014

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

Find a library that holds this journal:

Journal Language(s): English 

PBN Poland



Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2 Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase


Universal Impact Factor 1.78 for year 2012. (

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ)

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski