Post-stroke depression: predictors and prophylaxis

T. M. Muratova, D. M. Khramtsov, O. M. Stoyanov, Yu. M. Vorokhta, M. S. Vikarenko, G. G. Kozlova

Abstract


The purpose of the study was to evaluate the effectiveness of prevention of post-stroke depression in patients with acute cerebrovascular accident
It was shown that the incidence of PID in patients with ischemic stroke exceeds 30%. In assessing the role of various risk factors among the examined patients with PID, the prevalence of male patients (OR = 1.3 (1.1-1.5)), under the age of 55 (1.7 (1.3-1.9 )), with indications in the history of episodes of depression in the past (1.6 (1.4-1.8)), as well as alcohol abuse (1.2 (1.0-1.3)). In 31 (58.5%) there was a localization of focal ischemia in the frontal lobe of the dominant hemisphere. The use of both SIRS and an antidepressant with multimodal effect - vortioxetine was sufficiently effective in PID, but vortioxetin showing the best results - from 8,80,1 points to 6,20,1 points. The paper considers the expediency of the use of vorothoxetine in order to prevent PID in patients with ischemic stroke.

Keywords


: postnatal depression, ischemic stroke, diagnosis, treatment

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References


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