The selection of the amount of anthracene derivatives from raw materials of plant origin and the study of their influence on the rat periodontal

S. A. Schneider, O. V. Suslova, E. K. Tkachenko, K. V. Nikolaenko


The article presents a new method of ethanol extraction of anthracene derivatives from the herb St. John's wort, the total content of which was evaluated using a calibration graph. The drug improved mineral metabolism, showed anti-inflammatory effects in the bone tissue of the periodontal rats.


laboratory technology, anthracene derivatives, Hypericum perforatum grass, mineral metabolism, ethanol

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Inhibition of prostaglandin E2 production by anti-inflammatory hypericum perforatum extracts and constituents in RAW264.7 mouse macrophage cells. [Kimberly D.P. Hammer, Matthew L. Hillwig, Avery K.S. Solco, Philip M. Dixon, Kathleen Delate , Patricia A. Murphy, Eve S. Wurtele, Diane F. Birt]. J. Agric.Food Chem.: 2007: 55: 7323-7331.

Anastasia Karioti, Anna Rita Bilia. Hypericins as potential leads for new therapeutics. Int. j. Mol.Sci: 2010:11: 562-594.

Pseudohypericin is necessary for the light-activated inhibition of prostaglandin E2 pathways by a 4 component system mimicking an Hypericum perforatum fraction [Kimberly D.P. Hammer, Matthew L. Hillwig, Jeffrey D. Neighbors, Young-Je Sim, Marian L. Kohut, David F. Wiemer, Eve S. Wurtele, Diane F. Birt]. Phytochemistry.: 2008 (9): 69(12): 2354-2362.

Vladimirov Yu.A. , Archakov A. I. Perekisnoe okislenie lipidov v biologicheskix membranax. M.: Nauka.: 1972: 230. (in Russian)

Pravdivtseva O. E. Issledovaniya po obosnovaniyam novyih podhodov k standartizatsii syirya i preparatov Zveroboya prodyiryavlennogo. Himiya rastitelnogo syirya. : 2008: 1:. 81-86. (in Russian)

Tkachenko E. K. SposIb otrimannya vodnogo polIfenolnogo ekstraktu z travi derevIyu. / E. Tkachenko, S. NosIychuk, N. Novoselska // Patent №55011 vId 11.10.2010 (in Ukrainian)



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Journal of Education, Health and Sport formerly Journal of Health Sciences

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The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

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