Long-lasting stress, burnout syndrome, aging, and risk of Alzheimer's Disease

Emilia Mikołajewska, Dariusz Mikołajewski

Abstract


Burnout is defined as an excessive stress reaction to environment characterized by emotional and physical exhaustion, coupled with a sense of frustration and failure. Work-related stress, especially low job control and low social support, may increase the risk of dementia, especially AD. Aim of the paper is a better understanding of the complex nature of th long-lasting stress and professional burnout to early symptoms of the AD onset. Identification of mechanisms underying of such associations may help to develop more effective therapeutic strategies better tailored to patient’s profile. Despite efforts of scientists and clinicians objective diagnostic criteria and influence of burnout syndrome to AD remain ambiguous, making it difficult to recognize transition to early stage of AD. Additional longitudinal research is needed for determining what mediates the stress, burnout, and AD association, including both genders and not yet known risk factors.

Keywords


burnout syndrome; elderly people; compensation; mental disorders; occupational diseases; prevention

Full Text:

PDF

References


https://www.ncbi.nlm.nih.gov/mesh/?term=burnout - access January 16th, 2019.

Lastovkova A, Carder M, Rasmussen HM, Sjoberg L, Groene GJ, Sauni R, Vevoda J, Vevodova S, Lasfargues G, Svartengren M, Varga M, Colosio C, Pelclova D. Burnout syndrome as an occupational disease in the European Union: an exploratory study. Ind Health. 2018; 56(2):160-165.

Johansson L. Can stress increase Alzheimer's disease risk in women? Expert Rev Neurother. 2014; 14(2):123-5.

Masiak J., Kuspit M., Surtel W., Jarosz M. J. Stress, coping styles and personality tendencies of medical students of urban and rural origin. Ann Agr Env Med. 2014; 21(1):189-193.

Johansson L., Guo X., Waern M., Ostling S., Gustafson D., Bengtsson C., Skoog I. Midlife psychological stress and risk of dementia: a 35-year longitudinal population study. Brain. 2010; 133(Pt 8):2217-24.

Johansson L., Skoog I., Gustafson D. R., Olesen P. J., Waern M., Bengtsson C., Björkelund C., Pantoni L., Simoni M., Lissner L., Guo X. Midlife psychological distress associated with late-life brain atrophy and white matter lesions: a 32-year population study of women. Psychosom Med. 2012; 74(2):120-5.

Johansson L., Guo X., Hällström T., Norton M. C., Waern M., Ostling S., Bengtsson C., Skoog I. Common psychosocial stressors in middle-aged women related to longstanding distress and increased risk of Alzheimer's disease: a 38-year longitudinal population study. BMJ Open. 2013; 3(9):e003142.

Johansson L., Guo X., Duberstein P. R., Hällström T.. Waern M., Ostling S., Skoog I. Midlife personality and risk of Alzheimer disease and distress: a 38-year follow-up. Neurology. 2014; 83(17):1538-44.

Caselli R. J., Coon E. A., Johansson L. Midlife personality and risk of Alzheimer disease and distress: A 38-year follow-up. Neurology. 2015; 85(3):298-9.

Johansson L., Kern S., Zetterberg H., Blennow K., Börjesson-Hansson A., Rosengren L., Guo X., Skoog I. Midlife Stress in Relation to Late-Life Cerebrospinal Fluid Biomarkers of Alzheimer's Disease: A 25-Year Follow-Up Study. Dement Geriatr Cogn Disord. 2018; 46(1-2):90-99.

Lemche E. Early Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic Review. Curr Genomics. 2018; 19(7):522-602.

Hasselgren C., Dellve L., Ekbrand H., Zettergren A., Zetterberg H., Blennow K., Skoog I., Halleröd B. Socioeconomic status, gender and dementia: The influence of work environment exposures and their interactions with APOE 4. SSM Popul Health. 2018; 5:171-179.

Wojcik G. M., Masiak J., Kawiak A., Kwasniewicz L., Schneider P., Polak N., Gajos-Balinska A. Mapping the Human Brain in Frequency Band Analysis of Brain Cortex Electroencephalographic Activity for Selected Psychiatric Disorders. Front Neuroinform 2018; 12:73 .

Wojcik G. M., Masiak J., Kawiak A., Schneider P., Kwasniewicz L., Polak N., Gajos-Balinska A. New Protocol for Quantitative Analysis of Brain Cortex Electroencephalographic Activity in Patients With Psychiatric Disorders. Front Neuroinform 2018; 12:27.

Bisht K., Sharma K., Tremblay M. È. Chronic stress as a risk factor for Alzheimer's disease: Roles of microglia-mediated synaptic remodeling, inflammation, and oxidative stress. Neurobiol Stress. 2018; 9:9-21.

Chow Y. K., Masiak J., Mikołajewska E., Mikołajewski D., Wójcik G. M., Wallace B., Eugene A., Olajossy M. Limbic brain structures and burnout - A systematic review. Adv Med. Sci. 2018; 63(1):192-198.




DOI: http://dx.doi.org/10.5281/zenodo.2598872

Refbacks

  • There are currently no refbacks.




Copyright (c) 2019 © The Author(s)

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)