Pathophysiological concepts of the syndrome of chronic fatigue and clinical features as a basis for building physical rehabilitation programs

Nadezhda Bogdanovska, Iryna Kalonova, Natalia Pozmogova

Abstract


The syndrome of chronic fatigue is an extremely urgent and complex problem of modern medicine due to the widespread prevalence in the population, with a clear tendency to a steady increase in the incidence. Purpose: to determine the pathophysiological concepts of the syndrome of chronic fatigue. Methods of research: analysis of scientific literature, synthesis and generalization. Results. The syndrome of chronic fatigue is a disease with a complex pathogenesis involving deep disorders of the regulation of the central nervous system and immune system, disorders of cellular energy metabolism, ion transport and cardiovascular disorders. Infectious-inflammatory, psychoneurological and vegetative-endocrine complexes of sympoms are characteristic for this disease. Unlike other diseases of civilization, no specific causative agent has been identified and no clear connection has been established with genetic, hereditary, environmental factors. There are only theories of the pathogenesis of the syndrome of chronic fatigue and a number of factors that increase the possibility of its occurrence. The most popular are infectious (viral), immune and endocrine theories. Conclusions: Complex pathophysiological features of the syndrome of chronic fatigue cause the need for an integrated system approach to diagnosis, treatment and prevention of this disease, including physical rehabilitation.

Keywords


chronic fatigue syndrome, postvirus fatigue syndrome, weakness, etiology, immunity, virus, endocrinology

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References


Vagaytseva Ye. A. Sostoyaniye psikhofunktsional'noy sfery i immunnoy sistemy u bol'nykh sindromom khronicheskoy ustalosti i ikh dinamika pod vliyaniyem primeneniya polioksidoniya i lechebnykh fizicheskikh faktorov kurorta: avtoref. dis. ... kand. med. nauk : 14.00.51. / Pyatigor. gos. nauch.-issled. in-t kurortologii. Pyatigorsk, 2009. 24 s.

Vagaytseva Ye.A. Nekotoryye osobennosti diagnostiki sindroma khronicheskoy ustalosti pri epidemiologicheskikh usloviyakh. «Molodezh'-Barnaulu» materialy nauchno-prakticheskoy konferentsii molodykh uchenykh (Barnaul, 2003). Barnaul, 2003. S. 195-196.

Danilenko O. V., Churilov L. P. Sindrom khronicheskoy ustalosti kak autoimmunnaya gipotalamopatiya i chelovecheskiy potentsial: klinicheskiye i patofiziologicheskiye aspekty. Zdorov'ye – osnova chelovecheskogo potentsiala: problemy i puti ikh resheniya. 2009. 4(1). S 203-213.

Didkovskiy H.A., Malasheikova U.K., Zuykov I.A., Gurskaya O.G., Sarsannya ZH.SH., Kompaneyets I.A., Ogurtsov D.P., Kazanova G.V., Khaylov H.A. Vozmozhnaya rol' IL-15 v razvitii patologii mozga pri mialgicheskom entsefalomiyelite/sindrome khronicheskoy ustalosti. Rossiyskiy allergologncheskiy zhurnal. 2013. №2. S. 82-83.

Didkovskiy H.A., Ogurtsov D.P., Malashenkova I.K., Khaylov H.A., Krynskiy S.A. Gerpesvirusnaya infektsiya pri mialgicheskom entsefalomiyelite. Poliklinika. 2016. №4. S. 18-22.

Dobrusina M. Ye., Khristenko K. YU. Organizatsiya truda i sindrom khronicheskoy ustalosti. Vestnik Tomskogo gosudarstvennogo universiteta, 2011. № 345. S 143-148.

Komarov S. G. Diagnostika sindroma khronicheskoy ustalosti i algoritm organizatsii meditsinskoy pomoshchi bol'nym s dannoy patologiyey. Vestnik Ivanovskoy meditsinskoy akademii. 2007. №3-4. C. 37-38.

Komarov S. G. Sindrom khronicheskoy ustalosti: rasprostranennost' i organizatsiya meditsinskoy pomoshchi: avtoref. dis. ... kand. med. nauk : 14.00.33 / Gos. in-t usovershenstvovaniya vrachey. Moskva, 2008. 24 s.

Moroz I.N., Podkolzin A.A. Novoye v diagnostike i lechenii sindroma khronicheskoy ustalosti. Profilaktika stareniya. 1999. №1. S. 45-47.

Ogurtsov D. P. Limfotropnyye gerpeticheskiye virusy kak markery mialgicheskogo entsefalomiyelita: avtoref. dis. ... kand. med. nauk : 14.03.09 / Ros. un-t druzhby narodov. Moskva, 2016. 24 s.

11. Pizova N. V. Klinika, diagnostika i lecheniye sindroma khronicheskoy ustalosti. Meditsinskiy sonet. 2015. №2. S. 20-24.

Artsimovich N.G., Galushina T.S. Sindrom khronicheskoy ustalosti. M.: Nauch. mir, 2002. 220 s.

Fomicheva Ye.Ye., Filatenkova T.A. Narusheniye funktsiy GGAKS v eksperimental'noy modeli sindroma khronicheskoy ustalosti. Psikhofarmakologiya i biologicheskaya narkologiya. 2008. T. 8. Vyp. 1–2, chast' 2. . 2380-2381.

Buchwald D., Komaroff A.L. Review of laboratory findings for patients with chronic fatigue syndrome. Rev Infect Dis. 1991. №13(1). С 12-18.

Clark L.V., White P.D. The role of deconditioning and therapeutic exercise in chronic fatigue syndrome (CFS). Journal of mental health. 2005. № 14(3). С. 237-252.

Grygus І.М., Petruk L.A. Assessment of indices of physical development and functional status of female students of a special medical group. Journal of Education, Health and Sport. 2015;5(10):158-169.

Kokhan S.T.. Pateyuk A.V., Mingalova M.S., Grygus I.M. Use hippotherapy in physical rehabilitation of patients with different pathologies. Journal of Education, Health and Sport. 2015;5(2):289-296.

Pagani M, Ospedale L. S. Chronic fatigue syndrome: a hypothesis focusing on the autonomic nervous system. Clin. Sci (Colch). 1999. № 96 (1). С. 117-125.




DOI: http://dx.doi.org/10.5281/zenodo.1470739

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