The role of undifferentiated connective tissue diseases in the development of ischemic-cervical insufficiency in pregnant women

O. M. Nosenko, Kamel Bakary

Abstract


The article analyzes clinical and anamnestic and biochemical markers of undifferentiated connective tissue diseases (UCTDs), the course of pregnancy and childbirth in 56 women with ischemic-cervical insufficiency (ICI) and 30 healthy pregnancies without ICI. The obtained data on the study of UCTDs point to its importance in the development of ICI along with other factors. The presence of pathology of connective tissue in the examined pregnant women can be assumed on the following factors: the pregravidar low Vargue index, the presence of phenotypic markers, diseases indicative of the presence of UCTDs, and the increase in the level of hydroxyproline in daily urine. Given the history of the particular pregnant woman, as well as the presence of markers of UCTDs, it is possible to predict the development of ICI with high probability. The findings indicate the need to examine women at high risk, with a threat or with miscarriage with the help of UCTDs markers, with the aim of taking measures for additional timely diagnosis and subsequent correction of ICI.

Keywords


pregnancy, collagen, undifferentiated connective tissue diseases, markers, hydroxyproline, ischemic-cervical insufficiency, childbirth

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References


Demidov RO, Lapshina SA, Yakupova SP, Mukhina RG. Connective tissue dysplasia: modern approaches to the clinic, diagnosis and treatment. Practical medicine. 2015; 4 (15). Innovative technologies in medicine. Rheumatology. 2015; 4 (15). URL: http://pmarchive.ru/displaziya-soedinitelnoj-tkani-sovremennye-podxody-k-klinike-diagnostike-i-lecheniyu/.

Evtushenko SK, Lisovsky EB, Evtushenko OS. Dysplasia of connective tissue in neurology and pediatrics. A guide for doctors. Donetsk: Zaslavsky, 2009. 361 p.

Frolov AL, Kulavsky VA, Nikiforova MV. The role of connective tissue markers in the development of ischemic-cervical insufficiency in pregnancy. Mother and child in Kuzbass. 2014; 3 (58): 54-56.

Lukina TS, Pavlov OG, Kozina EA. Management of pregnant women with undifferentiated connective tissue dysplasia. Bulletin of new medical technologies. Electronic edition. 2015. № 4. Publication 2-5. URL: http: //www.medtsu.tula.ru/ VNMT/Bulletin/E2015-4/5258.pdf. DOI: 10.12737 / 16165.

McKusick V A. Heritable disorders of connective tissue. St. Louis: C. V. Mosby Company, 1972 (4th cd.). 878 p.

Sergeeva Yas, Serebryakova ML. Determination of hydroxyproline in serum with experimental myocardial infarction and its correction. Youth Scientific Forum: Natural and Medical Sciences: electr. Sat. Art. by mat. XXI International. stud. scientific-practical. Conf. No. 2 (20). URL: https://nauchforum.ru/archive/ MNF_nature/2(20).pdf.

Shcherbyna MO, Mu'Avia Salem Nasser Almardat. New ways of optimizing the management of women with ischemic-cervical insufficiency. Collection of scientific works of the Association of Obstetricians-Gynecologists of Ukraine. Kiev: The Polygraph Plus, 2014: 315-317.

Shibelgut NM, Moses VG, Zakharov IS, Kolesnikova NB. The course of pregnancy and outcomes of genera women with undifferentiated forms of connective tissue dysplasia. Medicine in the Kuzbass. 2009; 4: 28-31.

Zhabchenko IA. Obstetrical tactics in case of Isthmiko-cervical insufficiency: the solution of the main and accompanying problems. Protection of motherhood and childhood. 2015;1(25): 58-65.




DOI: http://dx.doi.org/10.5281/zenodo.1342707

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