Disease severity and mean platelet volume in elderly patients with pulmonary embolism

Grzegorz Staśkiewicz, Piotr Piech, Elżbieta Siek, Sebastian Uhlig, Magdalena Zakościelna, Joanna Kurzepa, Piotr Przybylski, Jacek Baj, Jerzy Przegaliński, Elżbieta Czekajska-Chehab, Andrzej Drop


Elderly patients are at higher risk of venous thromboembolism, including pulmonary embolism. Furhtermore, clinical course is frequently more servere. Platelet parameters are of increasing interest in thrombosis research, including mean platelet volume, which is a recognized indicator of increased thrombotic activity.

The aim of the study was to compare severity of pulmonary embolism as measured by computed tomography, as well as mean platelet volume in younger and elderly patients.

Retrospective analysis of 150 patients data was performed. Both younger and older patients presented with similar pulmonary embolism severity, time since onset of symptoms, as well as d-dimer levels. Elderly patients, however presented with significantly wider pulmonary artery diameter and larger mean platelet volume were observed.

In older patients group, even at the same severity of PE, significant differences of both CT-derived and platelet parameters are present. 


pulmonary embolism, PE, platelet volmue

Full Text:



Montagnana, M., Favaloro, E. J., Franchini, M., Guidi, G. C., & Lippi, G. (2010). The role of ethnicity, age and gender in venous thromboembolism. Journal of thrombosis and thrombolysis, 29(4), 489-496.

Huang, J., Chen, Y., Cai, Z., & Chen, P. (2015). Diagnostic value of platelet indexes for pulmonary embolism. The American journal of emergency medicine, 33(6), 760-763.

Kostrubiec, M., Łabyk, A., Pedowska-Włoszek, J., et al. (2010). Mean platelet volume predicts early death in acute pulmonary embolism. Heart, 96(6), 460-465.

Qanadli, S. D., El Hajjam, M., Vieillard-Baron, A. et al. (2001). New CT index to quantify arterial obstruction in pulmonary embolism: comparison with angiographic index and echocardiography. American Journal of Roentgenology, 176(6), 1415-1420.

Konstantinides, S., Torbicki, A., Agnelli, G. et al. (2014). 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. Kardiologia Polska (Polish Heart Journal),72(11), 997-1053.

Heit, J. A., Silverstein, M. D., Mohr, D.N. et al. (2001). The epidemiology of venous thromboembolism in the community. Thrombosis and haemostasis, 86(1), 452-63.

Weberová, D., Weber, P., Kubesová, H., Meluzínová, H., Polcarová, V., Ambrosova, P., & Bieláková, K. (2012). Occurrence of pulmonary embolism among 260 in-patients of acute geriatric department aged 65+ years in 2005–2010. Adv Gerontol, 25(3), 506-512.

Piazza, G., Seddighzadeh, A., & Goldhaber, S. Z. (2008). Deep-vein thrombosis in the elderly. Clinical and Applied Thrombosis/Hemostasis, 14(4), 393-398.

Golpe, R., Pérez-de-Llano, L. A., Castro-Añón, O., Vázquez-Caruncho, M., González-Juanatey, C., Veres-Racamonde, A., ... & Fariñas, M. C. (2010). Right ventricle dysfunction and pulmonary hypertension in hemodynamically stable pulmonary embolism. Respiratory medicine, 104(9), 1370-1376.

Wiwanitkit, V. (2004). Plateletcrit, mean platelet volume, platelet distribution width: its expected values and correlation with parallel red blood cell parameters. Clinical and applied thrombosis/hemostasis, 10(2), 175-178.

Tong, M., Seth, P., & Penington, D. G. (1987). Proplatelets and stress platelets. Blood, 69(2), 522-528.

Bath, P., Algert, C., Chapman, N., & Neal, B. (2004). Association of mean platelet volume with risk of stroke among 3134 individuals with history of cerebrovascular disease. Stroke, 35(3), 622-626.

Yuri Gasparyan, A., Ayvazyan, L., P Mikhailidis, D., & D Kitas, G. (2011). Mean platelet volume: a link between thrombosis and inflammation?. Current pharmaceutical design, 17(1), 47-58.

Huang, J., Chen, Y., Cai, Z., & Chen, P. (2015). Diagnostic value of platelet indexes for pulmonary embolism. The American journal of emergency medicine, 33(6), 760-763.

Braekkan, S. K., Mathiesen, E. B., Njølstad, I., et al. (2010). Mean platelet volume is a risk factor for venous thromboembolism: the Tromsø study. Journal of Thrombosis and Haemostasis, 8(1), 157-162.

Peng, F., Zheng, W., Li, F., et al. (2017). Elevated mean platelet volume is associated with poor outcome after mechanical thrombectomy. Journal of neurointerventional surgery, neurintsurg-2016.

Norgaz, T., Hobikoglu, G., Aksu, H et al. (2004). The relationship between preprocedural platelet size and subsequent in-stent restenosis. Acta cardiologica, 59(4), 391-395.

Jaster, M., Horstkotte, D., Willich, T. et al. (2008). The amount of fibrinogen-positive platelets predicts the occurrence of in-stent restenosis. Atherosclerosis, 197(1), 190-196.

Riedl, J., Kaider, A., Reitter, E. M., et al. (2014). Association of mean platelet volume with risk of venous thromboembolism and mortality in patients with cancer. Thrombosis and haemostasis, 111(4), 670-678.

DOI: http://dx.doi.org/10.5281/zenodo.1052007


  • There are currently no refbacks.

Copyright (c) 2017 © The Authors(s)

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014


POL-index 2011 - 2014


BASE 2011 - 2014




Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI


Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland






Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.


ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski