Increased pre-diabetic blood glucose levels as a risk factor of elevated systolic, but not diastolic, arterial pressure

Monika Tadla, Justyna Magdalena Skolarczyk, Joanna Pekar, Anna Olszewska, Katarzyna Skórzyńska-Dziduszko

Abstract


Introduction. The Finnish Diabetes Risk Score (FINDRISC) assesses the 10-year type 2 diabetes risk in adults by identifying individuals with overweight or obesity, inadequate physical activity, poor nutrition, or a family or personal history of hyperglycemia.

Aim. The objective of the study was to analyze the effect of personal history of increased (pre-diabetic) venous blood glucose on body weight, waist circumference, the magnitude of arterial pressure, and the total FINDRISC score of randomly selected individuals.

Materials and methods. The study was conducted in years 2015/2016 on 190 individuals – 96 women and 94 men. We determined FINDRISC score and measured blood pressure twice. The results were analyzed in STATISTICA 10 at p < 0.05.

Results. Interestingly, subjects with personal history of increased blood glucose had significantly higher systolic blood pressure (p=0.03), but not diastolic blood pressure, than subjects with history of normoglycemia. Both waist circumference (p=0.01) and total FINDRISC scores (p<0.001) were significantly elevated in the first group. Subjects with personal history of increased venous blood glucose showed a strong tendency (p = 0.055) towards higher body mass index (BMI) values than subjects with history of normoglycemia.

Discussion. Cardiovascular autonomic dysfunction(CAD) seems to be a main reason for hypertension in early stages of glucose dysmetabolism.

Conclusion. Increased pre-diabetic blood glucose level is an important risk factor of elevated systolic pressure, whereas diastolic pressure seems to be not affected by this factor.


Keywords


FINDRISC; pre-diabetic blood glucose level; arterial hypertension

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References


Lindstrom J, Tuomilehto J. The diabetes risk score: a practical tool to predict type 2 diabetes risk. Diabetes Care 2003; 26 (3): 725-731.

Schwarz PE, Li J, Lindstrom J, Tuomilehto J. Tools for predicting the risk of type 2 diabetes in daily practice. Horm Metab Res, 2009; 41 (2): 86–97.

Duda-Król W, Moskal M, Pękała M et al. FINDRISC scale as a common tool to assess the risk of diabetes type 2. MEDtube Science Mar, 2016; Vol.IV (1).

International Diabetes Federation. IDF Diabetes Atlas, 7th edition 2015. International Diabetes Federation 2015 [cited 22.05.2017]. Available from URL: http://www.idf.org/diabetesatlas.

Tabák A, Herder Ch, RathmannW et al. Prediabetes: A high-risk state for developing diabetes. Lancet. 2012 Jun 16; 379(9833): 2279–2290.

Landsberg L, Young J.B. 1985. The influence of diet on the sympathetic nervous system. Neuroendocrine Perspectives 1985; 191-218.

Modan, M., H. Halkin, S. Almog et al. Hyperinsulinemia. A link between hypertension, obesity and glucose intolerance. J. Clin. Invest 1985; 75:809.

Anderson EA, Hoffman RP, Balon TW et al. Hyperinsulinemia Produces both Sympathetic Neural Activation and Vasodilation in Normal Humans. J Clin Invest 1991 Jun; 87(6): 2246–2252.

Petersen KF, Befroy D, Dufour S et al. Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance. Science. 2003 May 16; 300(5622): 1140–1142.

Rooney DP, Edgar JDM, Sheridan B et al: The effects of low dose insulin infusions on the renin angiotensin and sympathetic nervous systems in normal man. Eur J Clin Invest 1991. 21:430–435.

Dimova R, Tankova T, Chakarova N et al. Cardio-metabolic profile of subjects with early stages of glucose intolerance and cardiovascular autonomic dysfunction. Diabetes Res Clin Pract. 2017 Apr;126:115-121.

Luo WS, Guo ZR, Hu XS et al. Impact of dynamic change of waist circumference or body mass index in hypertension incidence. Zhonghua Yu Fang Yi Xue Za Zhi 2011 Nov; 45(11):1012-6.

Sowers JR, Standley PR, Ram JL, Scott et al. Hyperinsulinemia, Insulin Resistance, and Hyperglycemia: Contributing Factors in the Pathogenesis of Hypertension and Atherosclerosis. Am J Hypertens 1993; 6 (7_Pt_2): 260S-270S.




DOI: http://dx.doi.org/10.5281/zenodo.1001691

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