Estimation of probiotic and vitamine D efficiency in prophylactics of infectious diseases in premature infants

N. L. Aryaev, I. M. Shevchenko, T. Ya. Moskalenko, J. M. El Mezevgi, N. V. Shevchenko

Abstract


The objective: to study the efficacy of probiotic and vitamin D use in prophylaxis of infectious diseases in premature infants. Materials and methods. The reseach has been conducted on the base of theOdessaNationalMedicalUniversity– neonatal unit of the maternity hospital N 7 (Odessa). The I group consisted of  20 premature infants (PI) who got BioGiy drops. The II group conssted of 19 PI, who got BioGiy drops and vitamin D3. Control group- 23 PI who did not get the preparations mentioned above. At birth and at the age of 3-4 months complex immunological investigation was carried out. Every month the morbidity of PI was observed. Results. PI are more likely to suffer from infectious diseases, functional disorders of the gastrointestinal tract and hypovitaminosis D. The results obtained indicate a high effectiveness of probiotic with vitamin D3 use for the prevention of infectious diseases in PI. The greatest effect was observed in the prevention of skin infections and respiratory diseases of the upper respiratory tract as a reduction of respiratory episodes frequency, acceleration of recovery and lighter course of the disease. Also, the combination of probiotic and vitamin D has proven itself as a means of preventing hypovitaminosis D in PI.


Keywords


immunity, premature infant, probiotic, vitamin D, infectious disease

Full Text:

PDF

References


Katz J, LeeAC, Kozuki N, et al. Mortality risk in preterm and small-for-gestational-age infants in low-income and middle-income countries: a pooled country analysis. Lancet 2013; 382:417.

Patel RM, Kandefer S, Walsh MC, et al. Causes and timing on death on extremely premature on fants from 2000 through 2011. N Engl J Med 2015; 372:331.

Corchia C, Ferrante P, Da Frè M, et al. Cause-specific mortality of very preterm infants and antenatal events. J Pediatr 2013; 162:1125.

Strunk T., Doherty D., Jacques A., Simmer K., Richmond P., Kohan R., et al. Histologic chorioamnionitis is associated with reduced risk of late-onset sepsis in preterm infants. Pediatrics. 2012 Jan;129(1):e134-41. doi: 10.1542/peds.2010-3493.

Szekeres-Bartho J. Immunological relationship between the mother and the fetus. Int. Rev. Immunol. 2002 Nov-Dec;21(6):471-95.

Pertseva VA., et al. Features of humoral immunity in premature infants depending on the peculiarities of neonatal period //Rus Med J. - 2011. - №31. – P.1990-1994 (Rus.).

Klebanoff M, Keim S. Epidemiology: the changing face of preterm birth. Clin Perinatol. 2011;38:339–350. doi: 10.1016/j.clp.2011.06.006.

Dowling DJ, Levy O. Ontogeny of early life immunity. Trends Immunol. 2014;35:299–310.

Livshits KH. Role of intenstine microbiota and probiotics in pediatric //Herald for Modern Clinical Med. – 2013. – Vol. 6, iss. 1. – P. 41-44 (Rus.).

Frei R., Akdis M., O'Mahony. Prebiotics, probiotics, synbiotics, and the immune system: experimental data and clinical evidence. Curr Opin Gastroenterol. 2015;31(2):153-8.

Vieira A.T., Teixeira M.M,. Martins F.S. The role of probiotics and prebiotics in inducing gut immunity. Front Immunol. 2013;4:445.

Arianna A., Davide G., Giovanni B. et al. Probiotics for prevention of necrotizing enterocolitis in preterm infants: systematic review and meta-analysis. Italian Journal of Pediatrics. 2015; 41:89.

Кvashina LV. Immunomodulating effects of vitamin D in children // Health of a child. - 2013. - №7 (50). -P.134-138 (Rus.).

Beard J.A., Bearden A., Striker R. Vitamin D and the antiviral state // J. Clin. Virol. - 2011. - Vol. 50, № 3. - P. 194­200.

Karatekin G., Kaya A., Salihoglu O. et al. Association of subclinical vitamin D deficiency in newborns with acute lower respiratory infection and their mothers // Eur. J. Clin. Nutr. - 2009. - № 63(4). - Р. 473­477.

Yang J, Chen G, Wang D et al. Low serum 25-hydroxyvitamin D level and risk of urinary tract infection in infants // Medicine Baltimore. – 2016. - 95(27), - doi: 10.1371.

Natarajan C. K., Sankar M. J., Agarwal R. et al. Trial of Daily Vitamin D Supplementation in Preterm Infants // Pediatrics. – 2014. - Vol. 133, № 3. - P. 628-634.




DOI: http://dx.doi.org/10.5281/zenodo.824796

Refbacks

  • There are currently no refbacks.




Copyright (c) 2017 © The Author (s) 2017

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)