Features of premature infants immune system

N. L. Aryaev, V. G. Marichereda, I. M. Shevchenko, T. Ya. Moskalenko, J. M. El Mezevgi, N. V. Shevchenko

Abstract


Premature birth (PB) is the most important aspects in maternal and child health care. The frequency of PB and birth of immature infants is increasing and ranges from 4.0 to 15.0-20.0%. In Ukraineits frequency varies from 3.0% to 12.0%. Preterm infants account for 60-70% of early neonatal and 65-75% of infant mortality. The aim: to examine the main premature baby’s immune system indexes as it is the immune system state that determines survival of a newborn child, the peculiarity of its life in neonatal period, effectiveness of therapeutic and rehabilitation measures, as well as the degree of disability. There were two groups of premature children under study: the I group, n = 62 premature infants, the age of gestation 34-36 weeks without perinatal pathology. The IId group (control ) was represented by 15 healthy newborns, aged 38-40 weeks of gestation. The study was carried out in the first 3 days of the child's life by flow cytofluorometry. In premature infants, the immaturity of the immune system was noted in the form of  decrease in all indices of nonspecific immunity: the level of the complement component of C3, the level of immunoglobulins class A, G and M and the values of T-killers and B-lymphocytes.


Keywords


premature birth, premature child immune system, indexes of immune system.

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References


Born Too Soon: The Global Action Report on Preterm Birth. May 2012 - NewYork. http://www.who.int/pmnch/media/news/2012/201204_borntoosoon-report.pdf

About approval of the Instruction for criteria definition of perinatal period, life birth, fetal death, order of their registration: Order of the Ukrainian Ministry of health care, dated 29.03.2006 № 179 [electronic resource]. Access mode http://www.moz.gov.ua/ua/portal/dn_20060329_179.html (Ukr.)

Katz J, Lee AC, Kozuki N, et al. Mortality risk in preterm and small-for-gestational-age infants in low-income and middle-income countries: a pooled country analysis. Lancet 2013; 382:417.

Patel RM, Kandefer S, Walsh MC, et al. Causes and timing on death on extremely premature infants from 2000 through 2011 //. N Engl J Med.- 2015; 372:331.

Corchia C, Ferrante P, Da Frè M, et al. Cause-specific mortality of very preterm infants and antenatal events // J Pediatr.- 2013; 162:1125.

Strunk T., Doherty D., Jacques A., Simmer K., Richmond P., Kohan R., et al. Histologic chorioamnionitis is associated with reduced risk of late-onset sepsis in preterm infants // Pediatrics.- 2012 Jan;129(1):e134-41. doi: 10.1542/peds.2010-3493.

Szekeres-Bartho J. Immunological relationship between the mother and the fetus // Int. Rev. Immunol. - 2002 Nov-Dec;21(6):471-95.

Pertseva VA, et al. Features of humoral immunity of preterm new-borns depending on the features of neonatal period // Russian Med, J. – 2011. - №31. – P.1990-1994 (Rus.).

Klebanoff M, Keim S. Epidemiology: the changing face of preterm birth // ClinPerinatol.- 2011;38:339–350. doi: 10.1016/j.clp.2011.06.006.

Dowling DJ, Levy O. Ontogeny of early life immunity // Trends Immunol. -2014;35:299–310. doi: 10.1016/j.it.2014.04.007.




DOI: http://dx.doi.org/10.5281/zenodo.816283

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