Influence balneotherapy on spa Truskavets’ with taking Canephron® N on urina lithogenicity and its metabolic and neuroendocrine-immune accompaniments in patients with chronic pyelonephrite and cholecystite

Oleksandr V. Shulyak, Igor-Severyn S. Flyunt, Victor R. Flyunt, Vitaliǐ M. Fil’, Borys V. Hrinchenko, Oleh V. Snihur, Walery Zukow, Oksana R. Yanchiy, Igor L. Popovych

Abstract


Shulyak Oleksandr V., Flyunt Igor-Severyn S., Flyunt Victor R., Fil’ Vitaliǐ M., Hrinchenko Borys V., Snihur Oleh V., Zukow Walery, Yanchiy Oksana R., Popovych Igor L. Influence balneotherapy on spa Truskavets’ with taking Canephron® N on urina lithogenicity and its metabolic and neuroendocrine-immune accompaniments in patients with chronic pyelonephrite and cholecystite. Journal of Education, Health and Sport. 2015;5(11):453-465. ISSN 2391-8306. DOIhttp://dx.doi.org/10.5281/zenodo.34351

http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%2811%29%3A453-465

https://pbn.nauka.gov.pl/works/673673

Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011–2014http://journal.rsw.edu.pl/index.php/JHS/issue/archive

 

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© The Author (s) 2015;

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This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial

use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 25.09.2015. Revised 25.10.2015. Accepted: 24.11.2015.

 

INFLUENCE BALNEOTHERAPY ON SPA TRUSKAVETS’ WITH TAKING CANEPHRON® N ON URINA LITHOGENICITY AND ITS METABOLIC AND NEUROENDOCRINE-IMMUNE ACCOMPANIMENTS IN PATIENTS WITH CHRONIC PYELONEPHRITE AND CHOLECYSTITE

 

Oleksandr V. Shulyak1, Igor-Severyn S. Flyunt2, Victor R. Flyunt3,6, Vitaliǐ M. Fil’2,

Borys V. Hrinchenko3, Oleh V. Snihur3, Walery Zukow4, Oksana R. Yanchiy5, Igor L. Popovych6

 

1Scientic Reseach Institute of Urology, Kyiv, Ukraine   Avshulyak@yandex.ua

2Faculties of Biology and Physical Education, Ivan Franko Pedagogical University, Drohobych, Ukraine

iflyunt@bk.ru    fillvitalij@rambler.ru

3JSC “Dnipro-Beskyd”, Truskavets’, Ukraine   t.verdo@mail.ru

4Faculty of Physical Education, Health and Tourism, Kazimierz Wielki University, Bydgoszcz, Poland w.zukow@ukw.edu.pl

5Departament of Biology, OO Bohomolets’ National Medical University, Kyiv, Ukraine

6Laboratory of Balneology, OO Bohomolets’ Institute of Physiology NAS, Truskavets’-Kyiv, Ukraine

i.popovych@biph.kiev.ua

 

SUMMARY

Objective. We know that balneotherapy on spa Truskavets' did not significantly affect the parameters of urina Lithogenicity, including Ca/Mg ratio, so search for means of reducing urina Lithogenicity remains relevant. We also know that Phytopreparation Canephron® N recommended for inclusion in complex therapy of chronic pyelonephrite as effective elimination of infectious kidney inflammation, prevention of recurrence of inflammation and lithogenese. Aim: to find out the possibility of reducing urina Lithogenicity influenced balneotherapy on spa Truskavets' by additional taking Canephron® N. Results. Standardized balneotherapy not significantly affect urina Lithogenicity in patients with chronic pyelonephrite and cholecystite, even showed a trend to increase, while additional use Canephron® N significantly reduces urina Lithogenicity by reducing the concentration of Uric acid and downward trend Calcium. Reducing urina Lithogenicity accompanied by a decrease urina concentration Chloride and Potassium, and Baevskiy’s Activity Regulatory Systems Index, Asymmetry δ-, θ- and α-rhythms of background EEG and α-rhythm normalized Power Spectrum Density (PSD) in right loci Fp2, F8, T6 and O2, while HRV markers of vagal tone (RMSSD, pNN50, TI) also Frequency Deviation θ- and β-rhythms, Amplitude β- and δ-rhythms, δ-rhythm PSD in loci Fp2, F8, T3, T5, O1, O2, β-rhythm PSD in loci Fp1, F4 and θ-rhythm PSD in loci T3 and F7 rising. However, Canephron® N preventes or reverses increasing Uric acid plasma level, Mineralocorticoide Activity, Sympathetic tone, Baevskiy’s Stress Index and PSD ULF HRV also decreasing PSD VLF HRV. Concerning parameters of Immunity Canephron® N decreases blood level active T-Lymphocytes but increases level B-Lymphocytes, Stubnucleary Neutrophiles and total Leukocytes also prevents or reverses increasing CD16+ NK-Lymphocytes, CD8+ and Theophilinesensitive T-Lymphocytes, Monocytes and serum IgM also decreasing CD4+ T-Lymphocytes and Neutrophiles Phagocytose Count vs Staphylococcus aureus. In addition, Canephron® N potentiates increasing Parathyrine Activity, serum level IgG and Bactericidic Capacity of Neutrophiles vs Staphylococcus aureus also decreasing Urea and Creatinine plasma level, Sodium urina concentration and Neutrophiles Phagocytose Count vs Escherichia coli. Conclusion. Introduce Canephron® N into standard balneotherapeutic complex spa Truskavets’ contribute to decrease urina Lithogenicity accompanied by decreasing of HRV and EEG markers of chronic Stress and favorable modulation parameters of Immunity in patients with chronic pyelonephrite and cholecystite.

Keywords: lithogenicity of urina, EEG, HRV, immunity, spa Truskavets’, Canephron® N.


Keywords


lithogenicity of urina, EEG, HRV, immunity, spa Truskavets’, Canephron® N.

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References


Baevskiy RM, Ivanov GG. Heart Rate Variability: theoretical aspects and possibilities of clinical application [in Russian]. Ultrazvukovaya i funktsionalnaya diagnostika. 2001; 3: 106-127.

Barylyak LG, Kruhliy YuZ, Zukow W, Yanchiy OR, Popovych IL. Indicators, distinctive for women with different ovarian status and different responses streslimiting effect of bioactive water Naftussya spa Truskavets’. Journal of Education, Health and Sport. 2015; 5(3): 247-258.

Brundig P, Berg W, Schneider HJ. Stress und Harnsteinbildungsrisiko. I. Der Einfluss von Stress auf lithogene Harnsubstanzen. Urol. Int. 1981; 36(4): 199-207.

Brundig P, Berg W, Schneider HJ. Stress und Harnsteinbildungsrisiko. II. Der Einfluss von Stress auf litholytische Harnsubstanzen. Urol. Int. 1981; 36(4): 265-273.

Chebanenko OI, Chebanenko LO, Popovych IL. Multivariate Balneoeffects of Factors of Spa Truskavets’ and Forecasting [in Ukrainian]. Kyiv: UNESCO-SOCIO. 2012. 496 p.

Chebanenko OI, Flyunt IS, Popovych IL, Balanovs’kyi VP, Lakhin PV. Water Naftussya and Water-Salt Exchange [in Ukrainian]. Kyiv: Naukova dumka. 1997. 141 p.

Chebanenko OI, Popovych IL, Chebanenko LO. Adaptogenic Essence of Balneotherapy [in Ukrainian]. Kyiv: UNESCO-SOCIO. 2013. 380 p.

Douglas SD, Quie PG. Investigation of Phagocytes in Disease. Churchil. 1981. 110 p.

Dudnyk VM, Zvenyhorods’ka HYu. Experience with Phitopreparation "Canephron N" acute uncomplicated pyelonephritis in children [in Ukrainian]. Contemporary pediatrics. 2012; 4(44): 1-4.

Flyunt VR, Flyunt IS, Barylyak LG, Piskov GG, Yanchiy OR. Links of urine Са/Mg coefficient of Lithogenicity of some parameters of electrolyte exchange in patients spa Truskavets’ [in Ukrainian]. Medical Hydrology and Rehabilitation. 2013; 11(3): 43-49.

Goryachkovskiy АМ. Clinical Biochemistry [in Russian]. Odesa: Astroprint. 1998. 608 p.

Hrinchenko BV, Snihur OV, Flyunt VR, Zukow W. Relationships between urina lithogenicity and neuro-humoral immune factors in patients with chronic pyelonephrite and cholecystite. Journal of Education, Health and Sport. 2015; 5(5): 44-51.

Іvassivka SV, Popovych IL, Aksentiychuk BI, Bilas VR. Nature of Balneofactors Water Naftussya and the Essense its therapeutic and preventive Action [in Ukrainian]. Truskavets’: Truskavets’kurort. 1999. 125 p.

Іvassivka SV, Popovych IL, Aksentiychuk BI, Flyunt IS. Physiological Activity of Uric Acid and its Role in the mechanism of action of Water Naftussya [in Ukrainian]. Kyiv: Computerpress. 2004. 163 p.

Kaladze NN, Slobodyan YeI. Pathogenetically oriented method for optimizing rehabilitation treatment of children with chronic pyelonephritis [in Russian]. Contemporary pediatrics. 2012; 2(42): 1-6.

Kostyuk PG, Popovych IL, Іvassivka SV (editors). Chornobyl’, Adaptive and Defensive Systems, Rehabilitation [in Ukrainian]. Kyiv: Computerpress. 2006. 348 p.

Kozyavkina OV, Kozyavkina NV, Gozhenko OA, Gozhenko AI, Barylyak LG, Popovych IL. Bioactive Water Naftussya and Neuroendocrine-Immune Complex [in Ukrainian]. Kyiv: UNESCO-SOCIO. 2015. 349 p.

Lapovets’ LYe, Lutsyk BD. Handbook of Laboratory Immunology [in Ukrainian]. L’viv. 2002. 173 p.

Lavrenchuk OV, Korol’ LV, Driyans’ka VE., Bagdasarova IV. Phytoprophylaxis recurrence of pyelonephritis in children [in Ukrainian]. Contemporary pediatrics. 2013; 2(50):

Lukovych YuS, Popovych АI, Kovbasnyuk MM, Korolyshyn TA, Barylyak LG, Popovych IL. Neuroendocrine-immune accompaniment of diuretic effect of balneotherapy on spa Truskavets’ [in Ukrainian]. Pochki. Nyrky. Kidney. 2015; 2(12): 7-14.

Marfiyan OM, Korolyshyn TA, Barylyak LG, Kovbasnyuk MM, Yavors’kyi OV, Zukow W, Popovych IL. Neuroendocrine-immune and metabolic accompaniments of cholecystokinetic effects of balneotherapy on spa Truskavets’. Journal of Education, Health and Sport. 2015; 5(5): 21-30.

Pinchuk VG, Gluzman DF. Immunocytochemistry and Monoclonal Antibodies in Oncohematology [in Russian]. Kyiv: Naukova dumka. 1990. 230 p.

Popovych IL. Stresslimiting Adaptogene Mechanism of Biological and Curative Activity of Water Naftussya [in Ukrainian]. Kyiv: Computerpress. 2011. 300 p.

Popovych IL, Barylyak LG. Influence of course using of bioactive water Naftussya on stress level at women with endocrine and gynecological pathology [in Ukrainian]. Medical Hydrology and Rehabilitation. 2009; 7(3): 100-118.

Popovych IL, Flyunt IS, Alyeksyeyev OI, Barylyak LG, Bilas VR. Sanogenetic Principles of Rehabilitation on Spa Truskavets’ Urological Patients Chornobyl’ Cohort [in Ukrainian]. Kyiv: Computerpress. 2003. 192 p.

Popovych IL, Kozyavkina OV, Kozyavkina NV, Korolyshyn TA, Lukovych YuS, Barylyak LG. Correlation between Indices of the Heart Rate Variability and Parameters of Ongoing EEG in Patients Suffering from Chronic Renal Pathology. Neurophysiology. 2014; 46(2): 139-148.

Popovych IL, Lukovych YuS, Korolyshyn TA, Barylyak LG, Kovalska LB, Zukow W. Relationship between the parameters heart rate variability and background EEG activity in healthy men. Journal of Health Sciences. 2013; 3(4): 217-240.

Popovych IL, Vis’tak (Markevych) HI, Humega MD, Ruzhylo SV. Vegetotropic Effects of Bioactive Water Naftussya and their Neuroendocrine-Immune, Metabolic and Hemodynamic Accompaniments [in Ukrainian]. Kyiv: UNESCO-SOCIO. 2014. 163 p.

Sarychev LP, Sarychev YaV. The therapeutic potential of modern herbal medicine chronic calculous pyelonephritis in elderly and senile patients under long-term use [in Russian]. Men's Health. 2014; 4(51): 14-17.

Stetsenko HI, Beyda PA, Perchenko VP, Loyik IV, Flyunt IS, Yatsyuk VM. Resort Rehabilitation Victims of Chornobylian Accident [in Ukrainian].- Kyiv: Zdorovya. 1999. 45-57.

Tiselius HS. A biochemical basis for grouping of patients with urolithiasis. Europ. Urol. 1978; 4: 241-249.


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