Dynamics of interleukin-6 in early period in the early period after simulation skeletal, cranial and combined injuries

R. Levchuk, A. Gudyma, T. Dzetsiukh

Abstract


Levchuk R., Gudyma A., Dzetsiukh T. Dynamics of interleukin-6 in early period in the early period after simulation skeletal, cranial and combined injuries. Journal of Education, Health and Sport. 2015;5(9):694-699. ISSN 2391-8306. DOIhttp://dx.doi.org/10.5281/zenodo.32195

http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%289%29%3A694-699

https://pbn.nauka.gov.pl/works/657592

Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011–2014http://journal.rsw.edu.pl/index.php/JHS/issue/archive

 

Deklaracja.

Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie.

Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.

The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).

© The Author (s) 2015;

This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, Poland

Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,

provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License

(http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.

This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial

use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 02.08.2015. Revised 05.09.2015. Accepted: 29.09.2015.

 

UDK 612.017–02:616.71–001.3/6]-092.9

 

DYNAMICS OF INTERLEUKIN-6 IN EARLY PERIOD IN THE EARLY PERIOD AFTER SIMULATION SKELETAL, CRANIAL AND COMBINED INJURIES

 

R. Levchuk, A. Gudyma, T. Dzetsiukh

 

State higher institution I. Horbachevsky Ternopil State Medical University of the Ministry of Health of Ukraine

 

Summary

Simulation of mechanical injuries of various localization in the early period traumatic disease leads to the accumulation in serum IL-6. After application of the skeletal injuries observed vibrational dynamics rate of increase in the first – after 1 day, reduced to the level control – 3 days and again, but smaller in amplitude – after 7 days. In the dynamics of cranial injury rate increases significantly in 7 days compared to the control. After applying the combined trauma of the content in serum blood IL-6 1 day after reaching the maximum level and remains at that level to 7 days. After 3-7 days in this group figure significantly higher than in other groups, where modeled separately and individually skeletal, cranialin juries, this effect manifested their mutual encumbrance.

 

 

Key words: skeletal, cranial, cranioskeletal injury, interleukin-6, experiment.


Keywords


skeletal, cranial, cranioskeletal injury, interleukin-6, experiment.

Full Text:

PDF

References


Левчук Р. Д Роль ліпопероксидації та антиоксидантного захисту в патогенезі ураження стінки тонкої кишки в динаміці краніоскелетної травми / Р. Д. Левчук, І. М. Дейкало // Здобутки клінічної і експериментальної медицини. – 2013. – № 2. – С. 120-123.

Пат. 81107 Україна, МПК G 09 В 23/28. Спосіб моделювання політравми / Левчук Р. Д., Михайлюк І. А., Мерлєв Д. І. ; заявник і патентовласник Державний вищий навчальний заклад “Тернопільський державний медичний університет імені І. Я. Горбачевського” МОЗ УКраїни . – № u 201213575 ; заявл. 27.11.12 ; опубл. 25.06.13, Бюл. 12.

Профиль провоспалительных цитокинов у больных с изолированной черепно-мозговой травмой средней и тяжелой степени тяжести / Е. Е. Байкова, А. Х. Каде, Ф. А. Нехай [и др.] // Современные проблемы науки и образования. – 2014. – № 2. – [режим доступу] www.science-education.ru/116-12810 .

Пустовий О.Ю. Вміст інтерлейкінів в сироватці крові хворих з черепно-мозковою травмою залежно від виду травми // Український морфологічний альманах. – 2012. – Том 10, №4. – С. 169-171.

Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF / R. Schindler, J. Mancilla, S. Endres [et al.] // Blood. – 1990. – Vol. 75. – P. 40—47.

Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways /S.J. van Deventer, H. R. Buller, J. W. ten Gate [et al] // Blood. – 1990. – Vol. 76. – P. 2520—2526.

Interleukin-6 in surgery, trauma, and critical care part II: clinical implications / R. S. Jawa, S. Anillo, K. Huntoon [et al] // J Intensive Care Med. – 2011. – Vol. 26(2). – P. 73-87.

Is interleukin 6 an early marker of injury severity following major trauma in humans? / F. Gebhard, H. Pfetsch, G. Steinbach [et al] // Arch Surg. – 2000. – Vol. 135(3). – P. 291-295.

Heinrich P. C. Interleukin-6 and the acute phase response / P. C. Heinrich, J. V. Castell, T. Andus // Biochem J. – 1990. – Vol. 265. – P. 621—636.

Lyson К. The effect of interleukin-6 on pituitary hormone release in vivo and in vitro / K. Lyson, S. M. McCann // Neuroendocrinology. – 1991. – Vol. 54. – P. 262—266.

Merlev D. The peculiarities of antioxidant-prooxidant balance of kidney’s papillary layer in skeletal and craniocerebral injuries and their combinations [Electronic resourse] / D. Merlev, A. Gudyma // Journal of Health Sciences. – 2014. – Vol. 4, N 1. – P. 134–144. – Available from : http://journal.rsw.edu.pl/index.php/JHS/article/view/508.


Refbacks

  • There are currently no refbacks.




Copyright (c)



Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)