Model of lumbar spinal stenosis in the experiment

Oleg Perepechai, Georgiy Ivanov, Nik Novikov, Iakiv Fishchenko

Abstract


Perepechai O., Ivanov G., Novikov N., Fishchenko I. Model of lumbar spinal stenosis in the experiment. Journal of Education, Health and Sport. 2015;5(7):171-178. ISSN 2391-8306. DOI 10.5281/zenodo.19735

http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%287%29%3A171-178

https://pbn.nauka.gov.pl/works/581310

http://dx.doi.org/10.5281/zenodo.19735

Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive

 

Deklaracja.

Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie.

Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.

The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).

© The Author (s) 2015;

This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, Poland

Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,

provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License

(http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.

This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial

use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 21.04.2015. Revised 28.05.2015. Accepted: 30.06.2015.

 

MODEL OF LUMBAR SPINAL STENOSIS IN THE EXPERIMENT

 

O. Perepechai1, G. Ivanov2, N. Novikov3, I. Fishchenko1

 

1State University “Institute of Traumatology and Orthopedics of NAMS of Ukraine”, Kiev, Ukraine

2State University “Professor M. Sitenko’s Institute of Spine and Joint Pathology of NAMS of Ukraine”, Kharkov, Ukraine

3Medical Academy named after S.I. Georgievsky of Vernadsky CFU

 

Abstracts

The description of an experimental model of lumbar spinal stenosis on 20 rats. The experiment was symmetrical dissection of arc plates to the inside thin cortical layer plates, and then dissection of the latter. The middle part of the arc with the spinous processes of the vertebrae is separated from the rest of the arc, and articular processes. The separated middle part of the arc with yellow ligament is shifted in the ventral direction, reducing the size of the cavity of the spinal canal and fix the contacting bone edges with bone cement. Degenerative changes of the nerve roots were evaluated histologically by endoneural and epineural changes using a 7-point scale of G. Byrond and others.

In the studied group of animals 7 days after spinal canal stenosis simulations appeared degenerative changes of nerve fibers, but the degree is low, and there is virtually no endoneural inflammation. The epineurium determined expressed or gross changes, indicating epineural inflammatory processes. After 1 month. There appeared dystrophic and degenerative changes of nerve fibers of the overwhelming majority (over 75%). At a later date (3 months), endoneural change remained practically the same as in the 1th month after surgery, epineural violations were preserved, there were groups and single fibroblasts as a sign of epineural fibrosis, as well as portions of connective tissue neoplasms and hyalinosis.

 

Keywords: lumbar spinal stenosis, an experimental model.


Keywords


lumbar spinal stenosis, an experimental model.

Full Text:

PDF

References


Byrod G. Early effect of nucleus pulposis application on spinal root morphology and function / G. Byrod, B. Rydevik, C. Nortborg, K. Olmaker // Eur. Spine J. – 1998. – V. 7. – P. 445-449.

Cornefjord M. A model for chronic nerve root compression studies: presentation of porcine model for controlled, slow-onset compression with analyses of anatomical aspects, compression onset rate, and morphologic and neurophysiologic effects / M. Cornefjord, K. Sato, K. Olmarker, B. Rydevik // Spine. – 1997. – V. 22. – № 9. – P. 946-957.

Kobayashi S. Vasogenic edema induced by compression injury to the spinal root: distribution of intravenously injected protein tracers and gadolinum-enhanced magnetic resonance imaging / S. Kobayashi, H. Yoshizawa, Y. Hachiya, [et al.] // Spine. – 1993. – № 18. – P. 1410-1424.

Sekiguchi M. Experimental spinal stenosis relationship between degree of the cauda equina compression, neuropathology and pain // M. Sekiguchi, S. Kikuchi, R.R. Myers // Spine. – 2004. – V.29. – P. 1105-1111.

Watanabe K. Spinal stenosis: assessment of motor function, VEGF expression, and angiogenesis in an experimental model in the rat / K. Watanabe, S. Konno, M. Sekiguchi, S. Kikuchi // Eur. Spine J. – 2007. – V. 16. – P.1913-1918.

Yashihara K. Chronic compression model of the cauda equina: morphological and electrophysiological study / K. Yashihara, M. Murakami, K. Takahachi [et al.] // J.Orthop Science. – 1996. – V. 1. – P. 376-383.

Yamaguchi K. Behavioral and morphologic studies of the chronically compressed cauda equina: experimental model of lumbar spinal stenosis in the rat / K. Yamaguchi, M. Murakami, K. Takahachi [et al.] // Spine. – 1999. – V. 24. – P. 845-851.


Refbacks

  • There are currently no refbacks.




Copyright (c)



Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)